Novel psychoactive substances of interest for psychiatry

Cardiac arrest after ibogaine ingestion

(2014) L. Vlaanderen et al.   CLINICAL TOXICOLOGY

MT-45, a new psychoactive substance associated with hearing loss and unconsciousness

(2014) A. Helander et al.   CLINICAL TOXICOLOGY

Three months of methoxetamine administration is associated with significant bladder and renal toxicity in mice

(2014) P. I. Dargan et al.   CLINICAL TOXICOLOGY

Misuse and Abuse of Pregabalin and Gabapentin: Cause for Concern?

(2014) Fabrizio Schifano   CNS DRUGS

From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs

(2014) Hamilton Morris et al.   Drug Testing and Analysis

Characterization of a novel and potentially lethal designer drug(±)-cis-para-methyl-4-methylaminorex (4,4'-DMAR, or ‘Serotoni’)

(2014) Simon D. Brandt et al.   Drug Testing and Analysis

A 3-year review of new psychoactive substances in casework

(2014) Simon Elliott et al.   FORENSIC SCIENCE INTERNATIONAL

A large amount of new designer drug diphenidine coexisting with a synthetic cannabinoid 5-fluoro-AB-PINACA found in a dubious herbal product

(2014) Amin Wurita et al.   Forensic Toxicology

Is there something more about synthetic cannabinoids?

(2014) Luke Yip et al.   Forensic Toxicology

Evaluation of Quetiapine Abuse and Misuse Reported to Poison Centers

(2014) Wendy Klein-Schwartz et al.   Journal of Addiction Medicine

Four Postmortem Case Reports with Quantitative Detection of the Synthetic Cannabinoid, 5F-PB-22

(2014) George Behonick et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Nephrotoxic effects of designer drugs: synthetic is not better!

(2014) Randy L. Luciano et al.   Nature Reviews Nephrology

Alterations in the serotonin system in schizophrenia: A systematic review and meta-analysis of postmortem and molecular imaging studies

(2014) Sudhakar Selvaraj et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Acute Psychotic Episode Associated with the Intake of a Testosterone-Enhancer Herbal Mixture Purchased Online

(2014) L. Minervini et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: Emerging ‘Novel Psychoactive Drugs’

(2013) Warunya Arunotayanun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK

(2013) Vikas Kapil et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The K2/Spice Phenomenon: emergence, identification, legislation and metabolic characterization of synthetic cannabinoids in herbal incense products

(2013) Lisa K. Brents et al.   DRUG METABOLISM REVIEWS

Characterization of the pyrolysis products of methiopropamine

(2013) Emily D. Bouso et al.   Drug Testing and Analysis

Emerging Drugs of Abuse

(2013) Michael E. Nelson et al.   EMERGENCY MEDICINE CLINICS OF NORTH AMERICA

Effects of acute detoxification of the herbal blend ‘Spice Gold’ on dopamine D2/3 receptor availability: A [18F]fallypride PET study

(2013) Axel Rominger et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products

(2013) Nahoko Uchiyama et al.   Forensic Toxicology

Identification of a new synthetic cannabinoid in a herbal mixture: 1-butyl-3-(2-methoxybenzoyl)indole

(2013) Yujin Park et al.   Forensic Toxicology

Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products

(2013) Nahoko Uchiyama et al.   Forensic Toxicology

Drops of madness? Recreational misuse of tropicamide collyrium; early warning alerts from Russia and Italy

(2013) Francesco Saverio Bersani et al.   GENERAL HOSPITAL PSYCHIATRY

“Spiceophrenia”: a systematic overview of “Spice”-related psychopathological issues and a case report

(2013) Duccio Papanti et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

The 12-month prevalence and nature of adverse experiences resulting in emergency medical presentations associated with the use of synthetic cannabinoid products

(2013) Adam R. Winstock et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

The Synthetic Cannabinoid Withdrawal Syndrome

(2013) Nicholas Nacca et al.   Journal of Addiction Medicine

Toxicological Findings of Synthetic Cannabinoids in Recreational Users

(2013) R. Kronstrand et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Nauclea latifolia Smith (Rubiaceae) exerts antinociceptive effects in neuropathic pain induced by chronic constriction injury of the sciatic nerve

(2013) Germain Sotoing Taïwe et al.   JOURNAL OF ETHNOPHARMACOLOGY

K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure

(2013) Amy L. Patton et al.   JOURNAL OF FORENSIC SCIENCES

5-HT2A Receptors in the Feline Brain: 123I-5-I-R91150 Kinetics and the Influence of Ketamine Measured with Micro-SPECT

(2013) T. Waelbers et al.   JOURNAL OF NUCLEAR MEDICINE

Ischemic stroke after use of the synthetic marijuana "spice"

(2013) M. J. Freeman et al.   NEUROLOGY

Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators: Potential utility as antipsychotic medications

(2013) Drake Morgan et al.   NEUROPHARMACOLOGY

Glutamatergic Dysbalance and Oxidative Stress in In Vivo and In Vitro Models of Psychosis Based on Chronic NMDA Receptor Antagonism

(2013) Just Genius et al.   PLoS One

Spicing things up: synthetic cannabinoids

(2013) Max Spaderna et al.   PSYCHOPHARMACOLOGY

Utilisation du phenibut en France : à propos de deux cas provençaux

(2013) Corinne Schmitt et al.   THERAPIE

Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings

(2012) Maren Hermanns-Clausen et al.   ADDICTION

Simultaneous analysis of synthetic cannabinoids in the materials seized during drug trafficking using GC-MS

(2012) Hyeyoung Choi et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Serotonin Syndrome Associated With MDPV Use: A Case Report

(2012) Josh Mugele et al.   ANNALS OF EMERGENCY MEDICINE

Dose-Related Behavioral, Subjective, Endocrine, and Psychophysiological Effects of the κ Opioid Agonist Salvinorin A in Humans

(2012) Mohini Ranganathan et al.   BIOLOGICAL PSYCHIATRY

The clinical toxicology of gamma-hydroxybutyrate, gamma-butyrolactone and 1,4-butanediol

(2012) Leo J Schep et al.   CLINICAL TOXICOLOGY

Neurochemical profiles of some novel psychoactive substances

(2012) Les Iversen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

DNA sequence analyses of blended herbal products including synthetic cannabinoids as designer drugs

(2012) Jun Ogata et al.   FORENSIC SCIENCE INTERNATIONAL

URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products

(2012) Nahoko Uchiyama et al.   FORENSIC SCIENCE INTERNATIONAL

Changes in the prevalence of synthetic cannabinoids and cathinone derivatives in Japan until early 2012

(2012) Ruri Kikura-Hanajiri et al.   Forensic Toxicology

Phenazepam abuse in the UK: an emerging problem causing serious adverse health problems, including death

(2012) John Martin Corkery et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

Detection of JWH-018 and JWH-073 by UPLC-MS-MS in Postmortem Whole Blood Casework

(2012) K. G. Shanks et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

An Accidental Fatal Intoxication with Methoxetamine

(2012) Maria Wikström et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters

(2012) Simon Bulling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic Cannabinoid-Induced Psychosis: Two Adolescent Cases

(2012) Olumide O. Oluwabusi et al.   JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY

Suspected and Confirmed Fatalities Associated With Mephedrone (4-Methylmethcathinone, “Meow Meow”) in the United Kingdom

(2012) Fabrizio Schifano et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Kavalactones and the endocannabinoid system: The plant-derived yangonin is a novel CB1 receptor ligand

(2012) Alessia Ligresti et al.   PHARMACOLOGICAL RESEARCH

Magnolol Reduces Glutamate-Induced Neuronal Excitotoxicity and Protects against Permanent Focal Cerebral Ischemia Up to 4 Hours

(2012) Wei-Ting Lee et al.   PLoS One

Identifying emerging trends in recreational drug use; outcomes from the Psychonaut Web Mapping Project

(2012) Paolo Deluca et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55

(2012) Viktor Rempel et al.   ACS Medicinal Chemistry Letters

The “New” Marijuana

(2011) Daina L Wells et al.   ANNALS OF PHARMACOTHERAPY

A survey study to characterize use of Spice products (synthetic cannabinoids)

(2011) Ryan Vandrey et al.   DRUG AND ALCOHOL DEPENDENCE

The syntheses of 1-(2-thienyl)-2-(methylamino) propane (methiopropamine) and its 3-thienyl isomer for use as reference standards

(2011) D. Angelov et al.   Drug Testing and Analysis

Some new psychoactive substances: Precursor chemicals and synthesis-driven end-products

(2011) Michael Collins   Drug Testing and Analysis

Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2

(2011) A. Mir et al.   PEDIATRICS

Is There a Recreational Misuse Potential for Pregabalin Analysis of Anecdotal Online Reports in Comparison with Related Gabapentin and Clonazepam Data

(2011) Fabrizio Schifano et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Kava: A Comprehensive Review of Efficacy, Safety, and Psychopharmacology

(2010) Jerome Sarris et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Receptors and Channels Targeted by Synthetic Cannabinoid Receptor Agonists and Antagonists

(2010) R. Pertwee   CURRENT MEDICINAL CHEMISTRY

Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds

(2010) Sebastian Dresen et al.   JOURNAL OF MASS SPECTROMETRY

Inhibition of monoamine oxidase activity by cannabinoids

(2010) Zdeněk Fišar   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cerebral Vasculopathy After 4-Bromo-2,5-Dimethoxyphenethylamine Ingestion

(2010) Josiah B. Ambrose et al.   NEUROLOGIST

Overview of Amphetamine-Type Stimulant Mortality Data – UK, 1997–2007

(2010) Fabrizio Schifano et al.   NEUROPSYCHOBIOLOGY

Psychedelics and the Human Receptorome

(2010) Thomas S. Ray   PLoS One

Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues

(2010) Fabrizio Schifano et al.   PSYCHOPHARMACOLOGY

Near-Death States Reported in a Sample of 50 Misusers

(2010) Ornella Corazza et al.   SUBSTANCE USE & MISUSE

The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study

(2009) Teresa R. Franklin et al.   DRUG AND ALCOHOL DEPENDENCE

Trapped in the "K-hole"

(2009) Fabrizio Schifano et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter

(2009) Nicholas V. Cozzi et al.   JOURNAL OF NEURAL TRANSMISSION

The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

(2009) D. Fontanilla et al.   SCIENCE

Activation of Cannabinoid-1 Receptors Disrupts Sensory Gating and Neuronal Oscillation: Relevance to Schizophrenia

(2008) Mihály Hajós et al.   BIOLOGICAL PSYCHIATRY

Sceletium—A review update

(2008) N. Gericke et al.   JOURNAL OF ETHNOPHARMACOLOGY

“Research Chemicals”: Tryptamine and Phenethylamine Use Among High-Risk Youth

(2008) Bill Sanders et al.   SUBSTANCE USE & MISUSE

The behavioral pharmacology of hallucinogens

(2007) William E. Fantegrossi et al.   BIOCHEMICAL PHARMACOLOGY

Standard protecting groups create potent and selective κ opioids: Salvinorin B alkoxymethyl ethers

(2007) Thomas A. Munro et al.   BIOORGANIC & MEDICINAL CHEMISTRY