Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist

Repetitive mild traumatic brain injury with impact acceleration in the mouse: Multifocal axonopathy, neuroinflammation, and neurodegeneration in the visual system

(2016) Leyan Xu et al.   EXPERIMENTAL NEUROLOGY

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice

(2016) Natalie H. Guley et al.   JOURNAL OF NEUROTRAUMA

Opponent and bidirectional control of movement velocity in the basal ganglia

(2016) Eric A. Yttri et al.   NATURE

Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism

(2016) A. R. Jayakumar et al.   NEUROCHEMICAL RESEARCH

Prolonged hippocampal cell death following closed-head traumatic brain injury in rats

(2016) Shigeharu Tsuda et al.   NEUROREPORT

How microglia kill neurons

(2015) Guy C. Brown et al.   BRAIN RESEARCH

FDG-PET and NeuN-GFAP Immunohistochemistry of Hippocampus at Different Phases of the Pilocarpine Model of Temporal Lobe Epilepsy

(2015) Liang Zhang et al.   International Journal of Medical Sciences

Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate

(2015) Luis B. Tovar-y-Romo et al.   JOURNAL OF NEUROCHEMISTRY

Repetitive mild traumatic brain injury induces ventriculomegaly and cortical thinning in juvenile rats

(2015) Corey Goddeyne et al.   JOURNAL OF NEUROPHYSIOLOGY

From circuits to behaviour in the amygdala

(2015) Patricia H. Janak et al.   NATURE

Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury

(2015) Venkata Siva Sai Sujith Sajja et al.   Scientific Reports

Motor, Visual and Emotional Deficits in Mice after Closed-Head Mild Traumatic Brain Injury Are Alleviated by the Novel CB2 Inverse Agonist SMM-189

(2014) Anton Reiner et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reversal of reduced parvalbumin neurons in hippocampus and amygdala of Angelman syndrome model mice by chronic treatment of fluoxetine

(2014) Swetha K. Godavarthi et al.   JOURNAL OF NEUROCHEMISTRY

Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury

(2014) Peter S Amenta et al.   Journal of Neuroinflammation

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Repetitive Mild Traumatic Brain Injury Causes Optic Nerve and Retinal Damage in a Mouse Model

(2014) Radouil Tzekov et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanical response of brain tissue under blast loading

(2014) Kaveh Laksari et al.   Journal of the Mechanical Behavior of Biomedical Materials

Amygdala interneuron subtypes control fear learning through disinhibition

(2014) Steffen B. E. Wolff et al.   NATURE

Pathological circuit function underlying addiction and anxiety disorders

(2014) Andreas Lüthi et al.   NATURE NEUROSCIENCE

Encoding of fear learning and memory in distributed neuronal circuits

(2014) Cyril Herry et al.   NATURE NEUROSCIENCE

Reduced GABAergic Inhibition in the Basolateral Amygdala and the Development of Anxiety-Like Behaviors after Mild Traumatic Brain Injury

(2014) Camila P. Almeida-Suhett et al.   PLoS One

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes

(2014) Wing Yip Tam et al.   Scientific Reports

A Novel Closed-Head Model of Mild Traumatic Brain Injury Caused by Primary Overpressure Blast to the Cranium Produces Sustained Emotional Deficits in Mice

(2014) Scott A. Heldt et al.   Frontiers in Neurology

Subcortical volume analysis in traumatic brain injury: The importance of the fronto-striato-thalamic circuit in task switching

(2013) Inge Leunissen et al.   CORTEX

Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective

(2013) D. R. Namjoshi et al.   Disease Models & Mechanisms

Thy1-Expressing Neurons in the Basolateral Amygdala May Mediate Fear Inhibition

(2013) A. M. Jasnow et al.   JOURNAL OF NEUROSCIENCE

Antibody testing for brain immunohistochemistry: Brain immunolabeling for the cannabinoid CB2 receptor

(2013) Jean-Ha Baek et al.   JOURNAL OF NEUROSCIENCE METHODS

Effects of blast-induced neurotrauma on the nucleus accumbens

(2013) Venkata Siva Sai Sujith Sajja et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Inflammatory Consequences in a Rodent Model of Mild Traumatic Brain Injury

(2013) J. Regino Perez-Polo et al.   JOURNAL OF NEUROTRAUMA

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

New insights into the classification and nomenclature of cortical GABAergic interneurons

(2013) Javier DeFelipe et al.   NATURE REVIEWS NEUROSCIENCE

Integration of GABAergic Interneurons into Cortical Cell Assemblies: Lessons from Embryos and Adults

(2013) Giorgia Bartolini et al.   NEURON

Blast induces oxidative stress, inflammation, neuronal loss and subsequent short-term memory impairment in rats

(2013) H.J. Cho et al.   NEUROSCIENCE

Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects

(2013) Raj K. Gupta et al.   Frontiers in Neurology

Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

(2012) Alok Kumar et al.   BRAIN BEHAVIOR AND IMMUNITY

Temporal assessment of traumatic axonal injury in the rat corpus callosum and optic chiasm

(2012) Nisrine Zakaria et al.   BRAIN RESEARCH

Impaired axoplasmic transport is the dominant injury induced by an impact acceleration injury device: An analysis of traumatic axonal injury in pyramidal tract and corpus callosum of rats

(2012) Srinivasu Kallakuri et al.   BRAIN RESEARCH

Axonal pathology in traumatic brain injury

(2012) Victoria E. Johnson et al.   EXPERIMENTAL NEUROLOGY

Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans

(2012) Rajendra A. Morey et al.   HUMAN BRAIN MAPPING

The Relation Between Posttraumatic Stress Disorder and Mild Traumatic Brain Injury Acquired During Operations Enduring Freedom and Iraqi Freedom

(2012) Jeffrey J. Bazarian et al.   JOURNAL OF HEAD TRAUMA REHABILITATION

New perspectives on central and peripheral immune responses to acute traumatic brain injury

(2012) Mahasweta Das et al.   Journal of Neuroinflammation

A cannabinoid type 2 receptor agonist attenuates blood-brain barrier damage and neurodegeneration in a murine model of traumatic brain injury

(2012) Peter S. Amenta et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Therapy Development for Diffuse Axonal Injury

(2012) Douglas H. Smith et al.   JOURNAL OF NEUROTRAUMA

The group 2 metabotropic glutamate receptor agonist LY379268 rescues neuronal, neurochemical and motor abnormalities in R6/2 Huntington's disease mice

(2012) A. Reiner et al.   NEUROBIOLOGY OF DISEASE

The neuroinflammatory response in humans after traumatic brain injury

(2012) C. Smith et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Morphological and genetic activation of microglia after diffuse traumatic brain injury in the rat

(2012) T. Cao et al.   NEUROSCIENCE

Understanding the neuroinflammatory response following concussion to develop treatment strategies

(2012) Zachary R. Patterson et al.   Frontiers in Cellular Neuroscience

Early Survival of Comatose Patients after Severe Traumatic Brain Injury with the Dual Cannabinoid CB1/CB2 Receptor Agonist KN38-7271: A Randomized, Double-Blind, Placebo-Controlled Phase II Trial

(2012) Raimund Firsching et al.   Journal of Neurological Surgery Part A-Central European Neurosurgery

In vivo knockdown of GAD67 in the amygdala disrupts fear extinction and the anxiolytic-like effect of diazepam in mice

(2012) S A Heldt et al.   Translational Psychiatry

The dopamine and cAMP regulated phosphoprotein, 32kDa (DARPP-32) signaling pathway: A novel therapeutic target in traumatic brain injury

(2011) James W. Bales et al.   EXPERIMENTAL NEUROLOGY

Immune responses of microglia in the spinal cord: Contribution to pain states

(2011) Dominic Schomberg et al.   EXPERIMENTAL NEUROLOGY

A Mouse Model of Blast Injury to Brain: Initial Pathological, Neuropathological, and Behavioral Characterization

(2011) Vassilis E. Koliatsos et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Repetitive Closed-Skull Traumatic Brain Injury in Mice Causes Persistent Multifocal Axonal Injury and Microglial Reactivity

(2011) Yoshitsugu Shitaka et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Selective Suppression of Plasticity in Amygdala Inputs from Temporal Association Cortex by the External Capsule

(2011) A. Morozov et al.   JOURNAL OF NEUROSCIENCE

Corticospinal Motor Neurons and Related Subcerebral Projection Neurons Undergo Early and Specific Neurodegeneration in hSOD1G93A Transgenic ALS Mice

(2011) P. H. Ozdinler et al.   JOURNAL OF NEUROSCIENCE

Acute Effects of a Selective Cannabinoid-2 Receptor Agonist on Neuroinflammation in a Model of Traumatic Brain Injury

(2011) Melanie B. Elliott et al.   JOURNAL OF NEUROTRAUMA

Detection of Blast-Related Traumatic Brain Injury in U.S. Military Personnel

(2011) Christine L. Mac Donald et al.   NEW ENGLAND JOURNAL OF MEDICINE

CB2: Therapeutic target-in-waiting

(2011) Brady K. Atwood et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor

(2010) Masayuki Fujinaga et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Acute management of acquired brain injury part II: An evidence-based review of pharmacological interventions

(2010) Matthew J. Meyer et al.   BRAIN INJURY

Biomechanics of Concussion

(2010) David F. Meaney et al.   CLINICS IN SPORTS MEDICINE

Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas

(2010) Nephi Stella   GLIA

Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Stereology of cerebral cortex after traumatic brain injury matched to the Glasgow Outcome Score

(2009) William L. Maxwell et al.   BRAIN

Simulation of Blast-Induced Early-Time Intracranial Wave Physics leading to Traumatic Brain Injury

(2009) Paul A. Taylor et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Neocortical Post-Traumatic Epileptogenesis Is Associated with Loss of GABAergic Neurons

(2009) Sinziana Avramescu et al.   JOURNAL OF NEUROTRAUMA

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

Anxiety-like behavior is modulated by a discrete subpopulation of interneurons in the basolateral amygdala

(2009) W.A. Truitt et al.   NEUROSCIENCE

Switching on and off fear by distinct neuronal circuits

(2008) Cyril Herry et al.   NATURE

Biology and therapeutic potential of cannabinoid CB2receptor inverse agonists

(2007) C A Lunn et al.   BRITISH JOURNAL OF PHARMACOLOGY