β-caryophyllene andβ-caryophyllene oxide-natural compounds of anticancer and analgesic properties

Medicinal cannabis

(2015) Bridin Murnion   Australian Prescriber

β-Caryophyllene potently inhibits solid tumor growth and lymph node metastasis of B16F10 melanoma cells in high-fat diet–induced obese C57BL/6N mice

(2015) Jae In Jung et al.   CARCINOGENESIS

Physicochemical Characterization and Analgesic Effect of Inclusion Complexes of Essential Oil from Hyptis pectinata L. Poit Leaves with β-Cyclodextrin

(2015) Paula Menezes et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

(2015) Martin Ambrož et al.   MOLECULES

Essential Oil Composition, Antioxidant, Cytotoxic and Antiviral Activities of Teucrium pseudochamaepitys Growing Spontaneously in Tunisia

(2015) Saoussen Hammami et al.   MOLECULES

The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllene from the Essential Oil of Aquilaria crassna

(2015) Saad Dahham et al.   MOLECULES

Interaction of β-caryophyllene and β-caryophyllene oxide with phospholipid bilayers: Differential scanning calorimetry study

(2015) Maria Grazia Sarpietro et al.   THERMOCHIMICA ACTA

Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System

(2014) Andrea Chicca et al.   ACS Chemical Biology

In VitroandIn VivoCharacterization of the New Analgesic Combination Beta-Caryophyllene and Docosahexaenoic Acid

(2014) Paolo Fiorenzani et al.   Evidence-based Complementary and Alternative Medicine

Essential oil from Myrica rubra leaves inhibits cancer cell proliferation and induces apoptosis in several human intestinal lines

(2014) Lenka Langhasova et al.   INDUSTRIAL CROPS AND PRODUCTS

Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles

(2014) L. M. Zasadil et al.   Science Translational Medicine

β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products

(2013) Chulwon Kim et al.   APOPTOSIS

The cannabinoid CB2 receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain

(2013) A.-L. Klauke et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Modulating the endocannabinoid system in human health and disease - successes and failures

(2013) Pál Pacher et al.   FEBS Journal

β-caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase

(2013) Chulwon Kim et al.   MOLECULAR CARCINOGENESIS

The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice

(2013) L.I.G. Paula-Freire et al.   PHYTOMEDICINE

Analysis of chemical constituents and antinociceptive potential of essential oil of Teucrium Stocksianum bioss collected from the North West of Pakistan

(2012) Syed Muhammad Mukarram Shah et al.   BMC Complementary and Alternative Medicine

Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception

(2012) S. Katsuyama et al.   EUROPEAN JOURNAL OF PAIN

β-Caryophyllene, a Compound Isolated from the Biblical Balm of Gilead (Commiphora gileadensis), Is a Selective Apoptosis Inducer for Tumor Cell Lines

(2012) Eitan Amiel et al.   Evidence-based Complementary and Alternative Medicine

A Hexane Fraction of Guava Leaves (Psidium guajava L.) Induces Anticancer Activity by Suppressing AKT/Mammalian Target of Rapamycin/Ribosomal p70 S6 Kinase in Human Prostate Cancer Cells

(2012) Nae Hyung Ryu et al.   JOURNAL OF MEDICINAL FOOD

Pain as a global public health priority

(2011) Daniel S Goldberg et al.   BMC PUBLIC HEALTH

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

(2011) Kyung-Ran Park et al.   CANCER LETTERS

Chemical composition, antinociceptive and anti-inflammatory effects in rodents of the essential oil of Peperomia serpens (Sw.) Loud

(2011) B.G. Pinheiro et al.   JOURNAL OF ETHNOPHARMACOLOGY

Psychological approaches to understanding and treating arthritis pain

(2010) Francis J. Keefe et al.   Nature Reviews Rheumatology

Cannabinoids in the treatment of cancer

(2009) Amy Alexander et al.   CANCER LETTERS

Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark

(2009) M.J. Chavan et al.   PHYTOMEDICINE

Dietary docosahexaenoic and eicosapentaenoic acid: Emerging mediators of inflammation

(2009) Robert S. Chapkin et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The endocannabinoid system in obesity and type 2 diabetes

(2008) V. Di Marzo   DIABETOLOGIA

Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

(2008) J LOPICCOLO et al.   DRUG RESISTANCE UPDATES

Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons

(2008) Uma Anand et al.   PAIN

Beta-caryophyllene is a dietary cannabinoid

(2008) Jürg Gertsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs

(2007) Yu-Tang Tung et al.   BIORESOURCE TECHNOLOGY