β-caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase

Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo

(2012) P. Rajendran et al.   Cancer Prevention Research

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells

(2011) Radhamani Kannaiyan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

(2011) Ji Young Heo et al.   CANCER LETTERS

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

(2011) Kyung-Ran Park et al.   CANCER LETTERS

STAT-3 Inhibitors: State of the Art and New Horizons for Cancer Treatment

(2011) A. Lavecchia et al.   CURRENT MEDICINAL CHEMISTRY

Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors

(2011) Arun K Mankan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapy

(2011) Daniela Masciocchi et al.   Future Medicinal Chemistry

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

(2011) Muthu K. Shanmugam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF- B and STAT3 pathways in head and neck cancer cells

(2010) M. A. Macha et al.   CARCINOGENESIS

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

(2010) Peramaiyan Rajendran et al.   CLINICAL CANCER RESEARCH

Stat3 Orchestrates Tumor Development and Progression: The Achilles Heel of Head and Neck Cancers?

(2010) M. Masuda et al.   CURRENT CANCER DRUG TARGETS

Sunitinib Induces Apoptosis and Growth Arrest of Medulloblastoma Tumor Cells by Inhibiting STAT3 and AKT Signaling Pathways

(2010) F. Yang et al.   MOLECULAR CANCER RESEARCH

Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway byNanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma

(2010) Diana Cirstea et al.   MOLECULAR CANCER THERAPEUTICS

Sorafenib Induces Growth Arrest and Apoptosis of Human Glioblastoma Cells through the Dephosphorylation of Signal Transducers and Activators of Transcription 3

(2010) Fan Yang et al.   MOLECULAR CANCER THERAPEUTICS

Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

(2009) Bharat B. Aggarwal et al.   Annals of the New York Academy of Sciences

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line

(2009) Karnati R. Roy et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Guggulsterone, a Farnesoid X Receptor Antagonist, Inhibits Constitutive and Inducible STAT3 Activation through Induction of a Protein Tyrosine Phosphatase SHP-1

(2008) K. S. Ahn et al.   CANCER RESEARCH