Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients

Hemophagocytic lymphohistiocytosis (HLH): A heterogeneous spectrum of cytokine-driven immune disorders

(2015) Ellen Brisse et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cytokine balance and cytokine-driven natural killer cell dysfunction in systemic juvenile idiopathic arthritis

(2015) Anneleen Avau et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Inhibition of Natural Killer Cell Cytotoxicity by Interleukin-6: Implications for the Pathogenesis of Macrophage Activation Syndrome

(2015) Loredana Cifaldi et al.   Arthritis & Rheumatology

Update on research and clinical translation on specific clinical areas: From bench to bedside: How insight in immune pathogenesis can lead to precision medicine of severe juvenile idiopathic arthritis

(2014) Sebastiaan Vastert et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Natural killer cell activity and frequency of killer cell immunoglobulin-like receptors in children with different forms of juvenile idiopathic arthritis

(2014) Juan Zhou et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Genetic Defects in Cytolysis in Macrophage Activation Syndrome

(2014) Mingce Zhang et al.   Current Rheumatology Reports

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

Systemic juvenile idiopathic arthritis

(2012) Alberto Martini   AUTOIMMUNITY REVIEWS

CTen: a web-based platform for identifying enriched cell types from heterogeneous microarray data

(2012) Jason E Shoemaker et al.   BMC GENOMICS

Transient impairment of NK cell function in an infant born to a mother with adult-onset Still's disease: Perinatal effect of maternal IL-18

(2012) Masaki Shimizu et al.   CLINICAL IMMUNOLOGY

Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment

(2012) A Ravelli et al.   GENES AND IMMUNITY

Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis

(2012) Nicolino Ruperto et al.   NEW ENGLAND JOURNAL OF MEDICINE

Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis

(2012) Fabrizio De Benedetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Familial and Acquired Hemophagocytic Lymphohistiocytosis

(2011) G.E. Janka   Annual Review of Medicine

Unexpected Role for Granzyme K in CD56bright NK Cell-Mediated Immunoregulation of Multiple Sclerosis

(2011) W. Jiang et al.   JOURNAL OF IMMUNOLOGY

Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

(2011) Elizabeth D. Mellins et al.   Nature Reviews Rheumatology

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

The Interactions of Multiple Cytokines Control NK Cell Maturation

(2010) J. Brady et al.   JOURNAL OF IMMUNOLOGY

Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

(2010) M. Shimizu et al.   RHEUMATOLOGY

Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

(2010) Claas H Hinze et al.   ARTHRITIS RESEARCH & THERAPY

Subtype-specific peripheral blood gene expression profiles in recent-onset juvenile idiopathic arthritis

(2009) Michael G. Barnes et al.   ARTHRITIS AND RHEUMATISM

Defective phosphorylation of interleukin-18 receptor β causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis

(2009) Wilco de Jager et al.   ARTHRITIS AND RHEUMATISM

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Distribution of circulating cells in systemic juvenile idiopathic arthritis across disease activity states

(2009) Claudia Macaubas et al.   CLINICAL IMMUNOLOGY

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis

(2009) Sebastiaan J. Vastert et al.   RHEUMATOLOGY

Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis

(2008) Rachelle Donn et al.   ARTHRITIS AND RHEUMATISM

Mutations of the hemophagocytic lymphohistiocytosis–associated geneUNC13D in a patient with systemic juvenile idiopathic arthritis

(2008) Melissa M. Hazen et al.   ARTHRITIS AND RHEUMATISM

Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms

(2008) Kejian Zhang et al.   ARTHRITIS AND RHEUMATISM