Regulation of Effector Treg Cells in Murine Lupus

The therapeutic potential of regulatory T cells for the treatment of autoimmune disease

(2015) Jeffrey A Bluestone et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3+regulatory T cells in MRL/lprmice

(2014) Tomohiro Koga et al.   AUTOIMMUNITY

Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

(2014) J. Christoph Vahl et al.   IMMUNITY

Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1

(2014) Ian A. Parish et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I interferons directly inhibit regulatory T cells to allow optimal antiviral T cell responses during acute LCMV infection

(2014) Shivani Srivastava et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Continuous requirement for the TCR in regulatory T cell function

(2014) Andrew G Levine et al.   NATURE IMMUNOLOGY

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gene Expression Profiling Identifies IRF4-Associated Molecular Signatures in Hematological Malignancies

(2014) Ling Wang et al.   PLoS One

Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP3 receptor 1 promotes Ca2+ signaling in T cells

(2014) C. Fos et al.   Science Signaling

Interleukin-21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice

(2014) Yanna Ding et al.   Arthritis & Rheumatology

Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance

(2014) Iris K. Gratz et al.   Frontiers in Immunology

Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals

(2013) Xuguang Tai et al.   IMMUNITY

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

Metabolic regulation of organelle homeostasis in lupus T cells

(2012) Tiffany N. Caza et al.   CLINICAL IMMUNOLOGY

P-value-based regulatory motif discovery using positional weight matrices

(2012) H. Hartmann et al.   GENOME RESEARCH

DEF6, a Novel Substrate for the Tec Kinase ITK, Contains a Glutamine-rich Aggregation-prone Region and Forms Cytoplasmic Granules that Co-localize with P-bodies

(2012) Fiona Hey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity

(2012) Partha S. Biswas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+T reg cells

(2012) Jonathan M. Weiss et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

(2012) Peter T Sage et al.   NATURE IMMUNOLOGY

Follicular helper T cells in immunity and systemic autoimmunity

(2012) Joseph E. Craft   Nature Reviews Rheumatology

Differentiation and function of Foxp3+ effector regulatory T cells

(2012) Erika Cretney et al.   TRENDS IN IMMUNOLOGY

Regulatory T cells in systemic lupus erythematosus (SLE); Role of peptide tolerance

(2011) Priya Sawla et al.   AUTOIMMUNITY REVIEWS

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors

(2011) Vojo Deretic   CURRENT OPINION IN IMMUNOLOGY

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins

(2011) Martin Gamerdinger et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

(2011) Yeonseok Chung et al.   NATURE MEDICINE

Foxp3+ follicular regulatory T cells control the germinal center response

(2011) Michelle A Linterman et al.   NATURE MEDICINE

Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis

(2011) Jean-François Marquis et al.   PLoS Genetics

Natural regulatory T cells in autoimmunity

(2010) Elaine V. Lourenço et al.   AUTOIMMUNITY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

T cells as therapeutic targets in SLE

(2010) José C. Crispín et al.   Nature Reviews Rheumatology

SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+signaling in T cells

(2009) Stéphane Bécart et al.   IMMUNOLOGICAL REVIEWS

IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?

(2009) Partha S. Biswas et al.   IMMUNOLOGICAL REVIEWS

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Tyrosine-Phosphorylation-Dependent Translocation of the SLAT Protein to the Immunological Synapse Is Required for NFAT Transcription Factor Activation

(2008) Stéphane Bécart et al.   IMMUNITY

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

IRF-4-Binding Protein Inhibits Interleukin-17 and Interleukin-21 Production by Controlling the Activity of IRF-4 Transcription Factor

(2008) Qinzhong Chen et al.   IMMUNITY