Gene Expression Profiling Identifies IRF4-Associated Molecular Signatures in Hematological Malignancies

IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α

(2014) Xingxing Kong et al.   CELL

Genetic variants in PARP1 (rs3219090) and IRF4(rs12203592) genes associated with melanoma susceptibility in a Spanish population

(2013) Maria Peña-Chilet et al.   BMC CANCER

A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway

(2013) Christian Praetorius et al.   CELL

Interferon Regulatory Factor 4 Is Activated through c-Src-Mediated Tyrosine Phosphorylation in Virus-Transformed Cells

(2013) L. Wang et al.   JOURNAL OF VIROLOGY

Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma

(2012) Yibin Yang et al.   CANCER CELL

GBP-1 acts as a tumor suppressor in colorectal cancer cells

(2012) Nathalie Britzen-Laurent et al.   CARCINOGENESIS

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

New markers for minimal residual disease detection in acute lymphoblastic leukemia

(2011) E. Coustan-Smith et al.   BLOOD

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

(2011) I. Salaverria et al.   BLOOD

Interferon Regulatory Factor 4 (IRF-4) Targets IRF-5 to Regulate Epstein-Barr Virus Transformation

(2011) Dongsheng Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prospective Multicenter Phase II Trial of Systemic ADH-1 in Combination With Melphalan via Isolated Limb Infusion in Patients With Advanced Extremity Melanoma

(2011) Georgia M. Beasley et al.   JOURNAL OF CLINICAL ONCOLOGY

Oncogenic IRFs Provide a Survival Advantage for Epstein-Barr Virus- or Human T-Cell Leukemia Virus Type 1-Transformed Cells through Induction of BIC Expression

(2011) L. Wang et al.   JOURNAL OF VIROLOGY

ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility

(2011) Masao Maeda et al.   MOLECULAR BIOLOGY OF THE CELL

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

Malignant pirates of the immune system

(2011) Lixin Rui et al.   NATURE IMMUNOLOGY

IRF4 Variants Have Age-Specific Effects on Nevus Count and Predispose to Melanoma

(2010) David L. Duffy et al.   AMERICAN JOURNAL OF HUMAN GENETICS

NFAT and IRF Proteins Regulate Transcription of the Anti-HIV Gene,APOBEC3G

(2010) Melissa A. Farrow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging Roles of FAM14 Family Members (G1P3/ISG 6–16 and ISG12/IFI27) in Innate Immunity and Cancer

(2010) Venugopalan Cheriyath et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing

(2010) Victoria James et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MUM1/IRF4

(2010) Gabriela Gualco et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor-Initiated Apoptosis via Repression of FLICE-like Protein Expression

(2009) D. Yang et al.   CANCER RESEARCH

IRF4: Immunity. Malignancy! Therapy?

(2009) A. L. Shaffer et al.   CLINICAL CANCER RESEARCH

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?

(2009) Partha S. Biswas et al.   IMMUNOLOGICAL REVIEWS

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a

(2008) Shaun Rosebeck et al.   APOPTOSIS

Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome

(2008) B. Chetaille et al.   BLOOD

Cell cycle regulated phosphorylation of LIMD1 in cell lines and expression in human breast cancers

(2008) Christopher Jack Huggins et al.   CANCER LETTERS

Interferon Regulatory Factor 4 Is Involved in Epstein-Barr Virus-Mediated Transformation of Human B Lymphocytes

(2008) D. Xu et al.   JOURNAL OF VIROLOGY

Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas

(2008) A L Feldman et al.   LEUKEMIA

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE

Stromal Gene Signatures in Large-B-Cell Lymphomas

(2008) G. Lenz et al.   NEW ENGLAND JOURNAL OF MEDICINE

The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development

(2008) T. V. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon regulatory factor 4 and 8 in B-cell development

(2008) Runqing Lu   TRENDS IN IMMUNOLOGY