A targeted proteomic multiplex CSF assay identifies increased malate dehydrogenase and other neurodegenerative biomarkers in individuals with Alzheimer’s disease pathology

Osteopontin is Increased in the Cerebrospinal Fluid of Patients with Alzheimer's Disease and Its Levels Correlate with Cognitive Decline

(2017) Cristoforo Comi et al.   JOURNAL OF ALZHEIMERS DISEASE

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

Explorative and targeted neuroproteomics in Alzheimer's disease

(2015) Ann Brinkmalm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes

(2015) N K Magdalinou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cerebrospinal Fluid Peptides as Potential Parkinson Disease Biomarkers: A Staged Pipeline for Discovery and Validation

(2015) Min Shi et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay

(2015) Wendy E. Heywood et al.   Molecular Neurodegeneration

Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF

(2015) Daniel S. Spellman et al.   Proteomics Clinical Applications

Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer’s disease

(2015) Jae Ho Kim et al.   Scientific Reports

Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer’s disease in a memory clinic cohort

(2015) Maartje I. Kester et al.   Alzheimers Research & Therapy

Longitudinal Cerebrospinal Fluid Biomarker Changes in Preclinical Alzheimer Disease During Middle Age

(2015) Courtney L. Sutphen et al.   JAMA Neurology

Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

(2015) S J Kiddle et al.   Translational Psychiatry

A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer’s Disease

(2015) Wasim Khan et al.   PLoS One

Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls

(2014) Eduardo Martínez-Morillo et al.   ACTA NEUROPATHOLOGICA

The cerebrospinal fluid “Alzheimer profile”: Easily said, but what does it mean?

(2014) Flora H. Duits et al.   Alzheimers & Dementia

Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

(2014) Bruno Dubois et al.   LANCET NEUROLOGY

Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics

(2014) Kristin R Wildsmith et al.   Molecular Neurodegeneration

Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals

(2014) R W Paterson et al.   Translational Psychiatry

Quantitative mass spectrometry (SRM/MRM) for amyloid peptides, tau protein and apolipoprotein E in human cerebrospinal fluid for Alzheimer's disease diagnosis

(2013) Sylvain Lehmann et al.   Alzheimers & Dementia

Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer’s disease

(2013) Manja Lehmann et al.   BRAIN

Targeted human cerebrospinal fluid proteomics for the validation of multiple Alzheimer's disease biomarker candidates

(2013) Yong Seok Choi et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The Identification of New Biomarkers for Identifying and Monitoring Kidney Disease and Their Translation into a Rapid Mass Spectrometry-Based Test: Evidence of Presymptomatic Kidney Disease in Pediatric Fabry and Type-I Diabetic Patients

(2013) Victoria Manwaring et al.   JOURNAL OF PROTEOME RESEARCH

Comparison of Protein Immunoprecipitation-Multiple Reaction Monitoring with ELISA for Assay of Biomarker Candidates in Plasma

(2013) De Lin et al.   JOURNAL OF PROTEOME RESEARCH

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease

(2013) Yuan Sun et al.   MEDIATORS OF INFLAMMATION

Quantitative Label-Free Proteomics for Discovery of Biomarkers in Cerebrospinal Fluid: Assessment of Technical and Inter-Individual Variation

(2013) Richard J. Perrin et al.   PLoS One

Proteomic Changes in Cerebrospinal Fluid of Presymptomatic and Affected Persons Carrying Familial Alzheimer Disease Mutations

(2012) John M. Ringman   ARCHIVES OF NEUROLOGY

Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer’s disease

(2012) Anne M Fagan et al.   Biomarkers in Medicine

Relationship between baseline brain metabolism measured using [18F]FDG PET and memory and executive function in prodromal and early Alzheimer’s disease

(2012) Christian Habeck et al.   Brain Imaging and Behavior

The development of a peptide SRM-based tandem mass spectrometry assay for prenatal screening of Down syndrome

(2012) Wendy Heywood et al.   Journal of Proteomics

Multiplexing and multivariate analysis in neurodegeneration

(2012) Ulf Andreasson et al.   METHODS

Targeted proteomics

(2012) Vivien Marx   NATURE METHODS

Search for New Phenomena intt¯Events with Large Missing Transverse Momentum in Proton-Proton Collisions ats=7  TeVwith the ATLAS Detector

(2012) G. Aad et al.   PHYSICAL REVIEW LETTERS

In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

(2012) Kristin R. Wildsmith et al.   PLoS One

Cystatin C in Alzheimer's disease

(2012) Gurjinder Kaur et al.   Frontiers in Molecular Neuroscience

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The clinical diagnosis of early-onset dementias: diagnostic accuracy and clinicopathological relationships

(2011) Julie S. Snowden et al.   BRAIN

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

(2011) Richard J. Perrin et al.   PLoS One

Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis

(2011) Rebecca Craig-Schapiro et al.   PLoS One

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

Proteomics of human cerebrospinal fluid: Discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics

(2010) A.C. Kroksveen et al.   Journal of Proteomics

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

(2009) Leslie M. Shaw et al.   ANNALS OF NEUROLOGY

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

(2009) Terri A Addona et al.   NATURE BIOTECHNOLOGY

Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

(2008) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease

(2008) Oliver Wirths et al.   NEUROBIOLOGY OF AGING

Combined rCBF and CSF biomarkers predict progression from mild cognitive impairment to Alzheimer's disease

(2007) Oskar Hansson et al.   NEUROBIOLOGY OF AGING