Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

YKL-40 Is Elevated in Patients with Chronic Obstructive Pulmonary Disease and Activates Alveolar Macrophages

(2014) S. Letuve et al.   JOURNAL OF IMMUNOLOGY

Novel CSF biomarkers for Alzheimer’s disease and mild cognitive impairment

(2010) William T. Hu et al.   ACTA NEUROPATHOLOGICA

YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease

(2010) Rebecca Craig-Schapiro et al.   BIOLOGICAL PSYCHIATRY

The Neuroprotective Role of PEDF: Implication for the Therapy of Neurological Disorders

(2010) T. Yabe et al.   CURRENT MOLECULAR MEDICINE

Secretogranin III: a Bridge between Core Hormone Aggregates and the Secretory Granule Membrane

(2010) Masahiro HOSAKA et al.   ENDOCRINE JOURNAL

Synaptic Tagging and Capture: Differential Role of Distinct Calcium/Calmodulin Kinases in Protein Synthesis-Dependent Long-Term Potentiation

(2010) R. L. Redondo et al.   JOURNAL OF NEUROSCIENCE

Enzyme-inhibitor-like tuning of Ca2+ channel connectivity with calmodulin

(2010) Xiaodong Liu et al.   NATURE

Ceruloplasmin fragmentation is implicated in 'free' copper deregulation of Alzheimer disease

(2010) Rosanna Squitti et al.   Prion

Diagnostic Value of CSF Biomarker Profile in Frontotemporal Lobar Degeneration

(2009) Elisabeth Kapaki et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Decreased cerebrospinal fluid Aβ42correlates with brain atrophy in cognitively normal elderly

(2009) Anne M. Fagan et al.   ANNALS OF NEUROLOGY

A γ-secretase inhibitor decreases amyloid-β production in the central nervous system

(2009) Randall J. Bateman et al.   ANNALS OF NEUROLOGY

Cerebrospinal Fluid Biomarkers and Rate of Cognitive Decline in Very Mild Dementia of the Alzheimer Type

(2009) Barbara J. Snider et al.   ARCHIVES OF NEUROLOGY

Beta Amyloid in Alzheimer's Disease: Increased Deposition in Brain Is Reflected in Reduced Concentration in Cerebrospinal Fluid

(2009) Timo Grimmer et al.   BIOLOGICAL PSYCHIATRY

Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases

(2009) Guo Nan Yin et al.   BRAIN RESEARCH

Transthyretin: the servant of many masters

(2009) Joel N. Buxbaum et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Secretogranin III Is an Astrocyte Granin That Is Overexpressed in Reactive Glia

(2009) Sonia Paco et al.   CEREBRAL CORTEX

N-cadherin prodomain cleavage regulates synapse formationin vivo

(2009) Nazlie S. Latefi et al.   Developmental Neurobiology

Neurogranin enhances synaptic strength through its interaction with calmodulin

(2009) Ling Zhong et al.   EMBO JOURNAL

Cerebrospinal fluid tau and ptau181increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease

(2009) Anne M. Fagan et al.   EMBO Molecular Medicine

Induction of Hypertension and Peripheral Inflammation by Reduction of Extracellular Superoxide Dismutase in the Central Nervous System

(2009) Heinrich E. Lob et al.   HYPERTENSION

Pigment Epithelium-derived Factor Maintains Retinal Pigment Epithelium Function by Inhibiting Vascular Endothelial Growth Factor-R2 Signaling through γ-Secretase

(2009) Zsolt Ablonczy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor necrosis factor receptor-associated protein 1 regulates cell adhesion and synaptic morphology via modulation of N-cadherin expression

(2009) Kyoko Kubota et al.   JOURNAL OF NEUROCHEMISTRY

Carbonic Anhydrases CA4 and CA14 Both Enhance AE3-Mediated Cl--HCOFormula Exchange in Hippocampal Neurons

(2009) N. Svichar et al.   JOURNAL OF NEUROSCIENCE

Calpain-Mediated N-Cadherin Proteolytic Processing in Brain Injury

(2009) Y.-N. Jang et al.   JOURNAL OF NEUROSCIENCE

Carboxypeptidase E knockout mice exhibit abnormal dendritic arborization and spine morphology in central nervous system neurons

(2009) Alicja Woronowicz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Relationship of Cerebrospinal Fluid Markers to 11C-PiB and 18F-FDDNP Binding

(2009) N. Tolboom et al.   JOURNAL OF NUCLEAR MEDICINE

Lack of fibulin-3 alters regenerative tissue responses in the primary olfactory pathway

(2009) Jana Vukovic et al.   MATRIX BIOLOGY

Fibulin-3 Is Uniquely Upregulated in Malignant Gliomas and Promotes Tumor Cell Motility and Invasion

(2009) B. Hu et al.   MOLECULAR CANCER RESEARCH

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Cytoplasmic gelsolin increases mitochondrial activity and reduces Aβ burden in a mouse model of Alzheimer's disease

(2009) Desiree Antequera et al.   NEUROBIOLOGY OF DISEASE

Evidence for mitochondrial and cytoplasmic N-acetylaspartate synthesis in SH-SY5Y neuroblastoma cells

(2009) Peethambaran Arun et al.   NEUROCHEMISTRY INTERNATIONAL

Longitudinal prognostic value of serum "free" copper in patients with Alzheimer disease

(2009) R. Squitti et al.   NEUROLOGY

Relationships between biomarkers in aging and dementia

(2009) W. J. Jagust et al.   NEUROLOGY

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin

(2009) S. Nag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calsyntenins Mediate TGN Exit of APP in a Kinesin-1-Dependent Manner

(2009) Alexander Ludwig et al.   TRAFFIC

Angiotensins in Alzheimer's disease – friend or foe?

(2009) Patrick G. Kehoe et al.   TRENDS IN NEUROSCIENCES

YKL-40

(2008) Dennis L. Kolson   AMERICAN JOURNAL OF PATHOLOGY

YKL-40, a Marker of Simian Immunodeficiency Virus Encephalitis, Modulates the Biological Activity of Basic Fibroblast Growth Factor

(2008) Dafna Bonneh-Barkay et al.   AMERICAN JOURNAL OF PATHOLOGY

Protease Activation of α2-Macroglobulin Modulates a Chaperone-like Action with Broad Specificity

(2008) Katie French et al.   BIOCHEMISTRY

Nectin-like molecule 1 is a glycoprotein with a single N-glycosylation site at N290KS which influences its adhesion activity

(2008) Jing Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular mechanism for neuro-protective effect of prosaposin against oxidative stress: Its regulation of dimeric transcription factor formation

(2008) Takashi Ochiai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Transthyretin Accelerates Vascular Aβ Deposition in a Mouse Model of Alzheimer's Disease

(2008) Henny Wati et al.   BRAIN PATHOLOGY

Secretogranin II: a key AP-1-regulated protein that mediates neuronal differentiation and protection from nitric oxide-induced apoptosis of neuroblastoma cells

(2008) L Li et al.   CELL DEATH AND DIFFERENTIATION

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

(2008) Brit Mollenhauer et al.   EXPERIMENTAL NEUROLOGY

Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits

(2008) Alicja Woronowicz et al.   HIPPOCAMPUS

Human apolipoprotein A–I binds amyloid-β and prevents Aβ-induced neurotoxicity

(2008) Andréa C. Paula-Lima et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protein CutA Undergoes an Unusual Transfer into the Secretory Pathway and Affects the Folding, Oligomerization, and Secretion of Acetylcholinesterase

(2008) Dong Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretoneurin promotes neuroprotection and neuronal plasticity via the Jak2/Stat3 pathway in murine models of stroke

(2008) Woei-Cherng Shyu et al.   JOURNAL OF CLINICAL INVESTIGATION

Biogenesis and Transport of Secretory Granules to Release Site in Neuroendocrine Cells

(2008) Joshua J. Park et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Gene transfer of PEDF attenuates ischemic brain damage in the rat middle cerebral artery occlusion model

(2008) Tomomi Sanagi et al.   JOURNAL OF NEUROCHEMISTRY

N-cadherin-based adhesion enhances Aβ release and decreases Aβ42/40ratio

(2008) Kengo Uemura et al.   JOURNAL OF NEUROCHEMISTRY

The Neurotrophin-Inducible Gene Vgf Regulates Hippocampal Function and Behavior through a Brain-Derived Neurotrophic Factor-Dependent Mechanism

(2008) O. Bozdagi et al.   JOURNAL OF NEUROSCIENCE

Application of Targeted Quantitative Proteomics Analysis in Human Cerebrospinal Fluid Using a Liquid Chromatography Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Tandem Mass Spectrometer (LC MALDI TOF/TOF) Platform

(2008) Sheng Pan et al.   JOURNAL OF PROTEOME RESEARCH

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

(2008) Thuzar M Shin et al.   Molecular Neurodegeneration

An aberrant protein complex in CSF as a biomarker of Alzheimer disease

(2008) M. A. Lovell et al.   NEUROLOGY

CSF biomarkers in frontotemporal lobar degeneration with known pathology

(2008) H. Bian et al.   NEUROLOGY

mGluR1/5-Dependent Long-Term Depression Requires the Regulated Ectodomain Cleavage of Neuronal Pentraxin NPR by TACE

(2008) Richard W. Cho et al.   NEURON

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON

Transthyretin Protects against A-Beta Peptide Toxicity by Proteolytic Cleavage of the Peptide: A Mechanism Sensitive to the Kunitz Protease Inhibitor

(2008) Rita Costa et al.   PLoS One

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cadherin-8 and N-cadherin differentially regulate pre- and postsynaptic development of the hippocampal mossy fiber pathway

(2007) Iddil H. Bekirov et al.   HIPPOCAMPUS

Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease

(2007) A.H. Simonsen et al.   NEUROBIOLOGY OF AGING

Generation of a constitutively active fragment of PKN in microglia/macrophages after middle cerebral artery occlusion in rats

(2003) Takehiko Ueyama et al.   JOURNAL OF NEUROCHEMISTRY