The Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic Differentiation

SOX9 and the many facets of its regulation in the chondrocyte lineage

(2016) Véronique Lefebvre et al.   CONNECTIVE TISSUE RESEARCH

Regulation of bone and cartilage by adenosine signaling

(2016) Lauren C. Strazzulla et al.   Purinergic Signalling

Effects of cell–cell contact and oxygen tension on chondrogenic differentiation of stem cells

(2015) Bin Cao et al.   BIOMATERIALS

Inverse Regulation of Early and Late Chondrogenic Differentiation by Oxygen Tension Provides Cues for Stem Cell-Based Cartilage Tissue Engineering

(2015) Sophie Portron et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

(2015) E. Kozhemyakina et al.   DEVELOPMENT

MicroRNAs in Bone Balance and Osteoporosis

(2015) Junying Chen et al.   DRUG DEVELOPMENT RESEARCH

Adenosine A2A Receptors Mediate Anti-Inflammatory Effects of Electroacupuncture on Synovitis in Mice with Collagen-Induced Arthritis

(2015) Qi-hui Li et al.   Evidence-based Complementary and Alternative Medicine

The Role of Reactive Oxygen Species in Mesenchymal Stem Cell Adipogenic and Osteogenic Differentiation: A Review

(2015) Fatemeh Atashi et al.   STEM CELLS AND DEVELOPMENT

Digoxin and Adenosine Triphosphate Enhance the Functional Properties of Tissue-Engineered Cartilage

(2015) Eleftherios A. Makris et al.   TISSUE ENGINEERING PART A

Effect of Advanced Oxidation Protein Products on Articular Cartilage and Synovium in a Rabbit Osteoarthritis Model

(2015) Hui Yu et al.   Orthopaedic Surgery

Resveratrol protects rabbit articular chondrocyte against sodium nitroprusside-induced apoptosis via scavenging ROS

(2014) Qian Liang et al.   APOPTOSIS

Sokolic R, Maric I, Kesserwan C, et al. Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency. Blood. 2011;118(10):2688-2694.

(2014)   BLOOD

Mitochondrial Pathology in Osteoarthritic Chondrocytes

(2014) Longhuo Wu et al.   CURRENT DRUG TARGETS

Sox5 Is a DNA-Binding Cofactor for BMP R-Smads that Directs Target Specificity during Patterning of the Early Ectoderm

(2014) Kara Nordin et al.   DEVELOPMENTAL CELL

Effect of microRNA-145 on IL-1β-induced cartilage degradation in human chondrocytes

(2014) Bo Yang et al.   FEBS LETTERS

Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis

(2014) Giuseppe M. Campo et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes

(2014) SEON-MI YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The Influence of IL-10 and TNFα on Chondrogenesis of Human Mesenchymal Stromal Cells in Three-Dimensional Cultures

(2014) Michal Jagielski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mesenchymal Stem Cells From Different Murine Tissues Have Differential Capacity to Metabolize Extracellular Nucleotides

(2014) Isabele C. Iser et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Overexpression of Wnt11 promotes chondrogenic differentiation of bone marrow-derived mesenchymal stem cells in synergism with TGF-β

(2014) Shuang Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The role of mitochondrial reactive oxygen species in cartilage matrix destruction

(2014) Kendra N. Reed et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation

(2014) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic programming of mesenchymal stromal cells by oxygen tension directs chondrogenic cell fate

(2014) J. Leijten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FOXO3A Regulation by miRNA-29a Controls Chondrogenic Differentiation of Mesenchymal Stem Cells and Cartilage Formation

(2014) David Guérit et al.   STEM CELLS AND DEVELOPMENT

Roles of Hypoxia During the Chondrogenic Differentiation of Mesenchymal Stem Cells

(2014) Jin Shang et al.   Current Stem Cell Research & Therapy

Effects of Cartilage Oligomeric Matrix Protein on Bone Morphogenetic Protein-2-induced Differentiation of Mesenchymal Stem Cells

(2014) Peng Guo et al.   Orthopaedic Surgery

Transcription Factor Runx2 in the Low Bone Mineral Density of Girls with Adolescent Idiopathic Scoliosis

(2014) Wei-jun Wang et al.   Orthopaedic Surgery

The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds

(2013) Ville V. Meretoja et al.   BIOMATERIALS

Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway

(2013) Seon-Mi Yu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions

(2013) Kimberly L. Cooper et al.   NATURE

Sox9-Regulated miRNA-574-3p Inhibits Chondrogenic Differentiation of Mesenchymal Stem Cells

(2013) David Guérit et al.   PLoS One

Adenosine A2A receptor activation and hyaluronan fragment inhibition reduce inflammation in mouse articular chondrocytes stimulated with interleukin-1β

(2012) Giuseppe M. Campo et al.   FEBS Journal

Activation of Wnt Planar cell polarity (PCP) signaling promotes growth plate column formation in vitro

(2012) Rachel M. Randall et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

PCB126 induces apoptosis of chondrocytes via ROS-dependent pathways

(2012) H.-G. Lee et al.   OSTEOARTHRITIS AND CARTILAGE

Characteristic scapular and rib changes on chest radiographs of children with ADA-deficiency SCIDS in the first year of life

(2012) David Manson et al.   PEDIATRIC RADIOLOGY

Chondrogenesis of human mesenchymal stem cells mediated by the combination of SOX trio SOX5, 6, and 9 genes complexed with PEI-modified PLGA nanoparticles

(2011) Ji Sun Park et al.   BIOMATERIALS

Reactive Oxygen Species in Myocardial Reperfusion Injury: From Physiopathology to Therapeutic Approaches

(2011) Vincent Braunersreuther et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

There is no evidence that mitochondria are the main source of reactive oxygen species in mammalian cells

(2011) Guy C. Brown et al.   MITOCHONDRION

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

MicroRNA-145 Regulates Chondrogenic Differentiation of Mesenchymal Stem Cells by Targeting Sox9

(2011) Bo Yang et al.   PLoS One

Functional selectivity of adenosine receptor ligands

(2011) Dennis Verzijl et al.   Purinergic Signalling

SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression

(2011) Victor Y. L. Leung et al.   PLoS Genetics

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling

(2010) Anatoly A. Starkov   Annals of the New York Academy of Sciences

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification

(2010) T. Hattori et al.   DEVELOPMENT

The Regulation of Differentiation in Mesenchymal Stem Cells

(2010) Andrea Augello et al.   HUMAN GENE THERAPY

Wnt5b regulates mesenchymal cell aggregation and chondrocyte differentiation through the planar cell polarity pathway

(2010) Elizabeth W. Bradley et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Wnt/β-Catenin and Retinoic Acid Receptor Signaling Pathways Interact to Regulate Chondrocyte Function and Matrix Turnover

(2009) Rika Yasuhara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human mesenchymal stem cells: Influence of oxygen pressure on proliferation and chondrogenic differentiation in fibrin gluein vitro

(2009) Laura Baumgartner et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The Wnt/β-Catenin Pathway Interacts Differentially with PTHrP Signaling to Control Chondrocyte Hypertrophy and Final Maturation

(2009) Xizhi Guo et al.   PLoS One

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

(2008) Yong Pan et al.   DEVELOPMENTAL BIOLOGY

Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal

(2008) Amjad Javed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sox9 Inhibits Wnt Signaling by Promoting β-Catenin Phosphorylation in the Nucleus

(2008) Lilia Topol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxic expansion promotes the chondrogenic potential of articular chondrocytes

(2008) Rainer J. Egli et al.   JOURNAL OF ORTHOPAEDIC RESEARCH