A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications

Analysis of glycated serum proteins in type 2 diabetes patients with nephropathy

(2014) Mi-Ryung Kim et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus

(2014) M. J. Pena et al.   DIABETIC MEDICINE

Proteomics and diabetic nephropathy: what have we learned from a decade of clinical proteomics studies?

(2014) Massimo Papale et al.   JOURNAL OF NEPHROLOGY

Role of Podocyte B7-1 in Diabetic Nephropathy

(2014) P. Fiorina et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease

(2014) T.-H. Yoo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Enhanced glomerular Toll-like receptor 4 expression and signaling in patients with type 2 diabetic nephropathy and microalbuminuria

(2014) Daniela Verzola et al.   KIDNEY INTERNATIONAL

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

(2014) Xiaojie Wang et al.   KIDNEY INTERNATIONAL

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Predictive Significance of Kidney Myeloid-Related Protein 8 Expression in Patients with Obesity- or Type 2 Diabetes-Associated Kidney Diseases

(2014) Takashige Kuwabara et al.   PLoS One

Evaluation of Candidate Nephropathy Susceptibility Genes in a Genome-Wide Association Study of African American Diabetic Kidney Disease

(2014) Nicholette D. Palmer et al.   PLoS One

Genomic and Metabolomic Profile Associated to Microalbuminuria

(2014) Vannina G. Marrachelli et al.   PLoS One

Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury

(2014) Youqun Huang et al.   BMC Nephrology

Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs

(2013) Loredana Fiorentino et al.   ACTA DIABETOLOGICA

Urinary sediment miRNA levels in adult nephrotic syndrome

(2013) Gang Wang et al.   CLINICA CHIMICA ACTA

Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

(2013) Loredana Fiorentino et al.   EMBO Molecular Medicine

Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

(2013) Michelle B. Hookham et al.   FEBS Journal

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy

(2013) Ji Zhou et al.   GENE

D18S880 Microsatellite Polymorphism of Carnosinase Gene and Diabetic Nephropathy: A Meta-Analysis

(2013) Ji-Min Zhu et al.   Genetic Testing and Molecular Biomarkers

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

(2013) Michal Herman-Edelstein et al.   JOURNAL OF LIPID RESEARCH

Diabetic nephropathy induces changes in the proteome of human urinary exosomes as revealed by label-free comparative analysis

(2013) Irene Zubiri et al.   Journal of Proteomics

Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease

(2013) K. Sharma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice

(2013) Marpadga A. Reddy et al.   KIDNEY INTERNATIONAL

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

(2013) Kazuhiro Hasegawa et al.   NATURE MEDICINE

Family-Based Association Analysis Confirms the Role of the Chromosome 9q21.32 Locus in the Susceptibility of Diabetic Nephropathy

(2013) Marcus G. Pezzolesi et al.   PLoS One

Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes

(2013) Christos Argyropoulos et al.   PLoS One

Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy

(2013) Federica Barutta et al.   PLoS One

Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

(2013) M. Lucrecia Alvarez et al.   PLoS One

Urinary miR-29 Correlates with Albuminuria and Carotid Intima-Media Thickness in Type 2 Diabetes Patients

(2013) Hui Peng et al.   PLoS One

Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy

(2012) Akiyoshi Hirayama et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy

(2012) Eoin P. Brennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Urinary Proteomics for Early Diagnosis in Diabetic Nephropathy

(2012) P. Zurbig et al.   DIABETES

Novel Urinary Protein Biomarkers Predicting the Development of Microalbuminuria and Renal Function Decline in Type 1 Diabetes

(2012) D. Schlatzer et al.   DIABETES CARE

A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus

(2012) S. S. Roscioni et al.   DIABETOLOGIA

Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients

(2012) Jonghwa Jin et al.   Experimental Diabetes Research

Characterization of glomerular diseases using proteomic analysis of laser capture microdissected glomeruli

(2012) Anjali A Satoskar et al.   MODERN PATHOLOGY

Opening a treasure chest: glomerular proteome analyses of formalin-fixed paraffin-embedded kidney tissue in the investigation of diabetic nephropathy

(2012) A. Blutke   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Pilot Trial Assessing Urinary Gene Expression Profiling with an mRNA Array for Diabetic Nephropathy

(2012) Min Zheng et al.   PLoS One

Metabolomics: the final frontier?

(2012) Timothy D Veenstra   Genome Medicine

Diabetic nephropathy in type 2 diabetes: MPO T-764C genotype is associated with oxidative stress

(2012) Jana Makuc et al.   Open Life Sciences

Plasma esterified and non-esterified fatty acids metabolic profiling using gas chromatography–mass spectrometry and its application in the study of diabetic mellitus and diabetic nephropathy

(2011) Li-Da Han et al.   ANALYTICA CHIMICA ACTA

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

(2011) Carmen Sapienza et al.   Epigenetics

Wnt/β-Catenin Pathway in Podocytes Integrates Cell Adhesion, Differentiation, and Survival

(2011) Hideki Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The use of formalin fixed wax embedded tissue for proteomic analysis

(2011) L. D. Ralton et al.   JOURNAL OF CLINICAL PATHOLOGY

The TGF-  Route to Renal Fibrosis Is Not Linear: The miR-21 Viaduct

(2011) A. A. Eddy   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study)

(2011) F. M. van der Kloet et al.   Metabolomics

Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis

(2011) Shinya Nakatani et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Urinary Podocyte-Associated mRNA profile in Various Stages of Diabetic Nephropathy

(2011) Min Zheng et al.   PLoS One

Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy

(2011) M. Lucrecia Alvarez et al.   PLoS One

Phospholipidomic identification of potential plasma biomarkers associated with type 2 diabetes mellitus and diabetic nephropathy

(2011) Chao Zhu et al.   TALANTA

Differential Effects of MYH9 and APOL1 Risk Variants on FRMD3 Association with Diabetic ESRD in African Americans

(2011) Barry I. Freedman et al.   PLoS Genetics

Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy

(2010) Shuya Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

(2010) Christopher G Bell et al.   BMC Medical Genomics

Urine Proteome Analysis May Allow Noninvasive Differential Diagnosis of Diabetic Nephropathy

(2010) M. Papale et al.   DIABETES CARE

Genetic associations in diabetic nephropathy: a meta-analysis

(2010) A. L. Mooyaart et al.   DIABETOLOGIA

Loss of MicroRNA-192 Promotes Fibrogenesis in Diabetic Nephropathy

(2010) A. Krupa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A genome-wide association study for diabetic nephropathy genes in African Americans

(2010) Caitrin W. McDonough et al.   KIDNEY INTERNATIONAL

Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease

(2010) David M. Good et al.   MOLECULAR & CELLULAR PROTEOMICS

Epigenetic phenomena linked to diabetic complications

(2010) Luciano Pirola et al.   Nature Reviews Endocrinology

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

(2010) Stephanie J. Mihalik et al.   Obesity

Podocytic PKC-Alpha Is Regulated in Murine and Human Diabetes and Mediates Nephrin Endocytosis

(2010) Irini Tossidou et al.   PLoS One

Systematic Analysis of a Novel Human Renal Glomerulus-Enriched Gene Expression Dataset

(2010) Maja T. Lindenmeyer et al.   PLoS One

Multicentric Validation of Proteomic Biomarkers in Urine Specific for Diabetic Nephropathy

(2010) Alaa Alkhalaf et al.   PLoS One

Finding diabetic nephropathy biomarkers in the plasma peptidome by high-throughput magnetic bead processing and MALDI-TOF-MS analysis

(2010) Henning G. Hansen et al.   Proteomics Clinical Applications

Identification of diabetic nephropathy-selective proteins in human plasma by multi-lectin affinity chromatography and LC-MS/MS

(2010) Jung-Mo Ahn et al.   Proteomics Clinical Applications

Epithelial-Mesenchymal Transition as a Potential Explanation for Podocyte Depletion in Diabetic Nephropathy

(2009) Yukinari Yamaguchi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC–oaTOF-MS system

(2009) Jie Zhang et al.   ANALYTICA CHIMICA ACTA

Confirmation of Genetic Associations at ELMO1 in the GoKinD Collection Supports Its Role as a Susceptibility Gene in Diabetic Nephropathy

(2009) M. G. Pezzolesi et al.   DIABETES

Genome-Wide Association Scan for Diabetic Nephropathy Susceptibility Genes in Type 1 Diabetes

(2009) M. G. Pezzolesi et al.   DIABETES

Metabolomics Applied to Diabetes Research: Moving From Information to Knowledge

(2009) J. R. Bain et al.   DIABETES

Ultraviolet and tandem mass spectrometry for simultaneous quantification of 21 pivotal metabolites in plasma from patients with diabetic nephropathy

(2009) Jian-Fei Xia et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mouse Models of Diabetic Nephropathy

(2009) F. C. Brosius et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic Kidney Disease Prevalence Estimates among Racial/Ethnic Groups: The Multi-Ethnic Study of Atherosclerosis

(2008) H. Kramer et al.   Clinical Journal of the American Society of Nephrology

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Increased renal gene transcription of protein kinase C-β in human diabetic nephropathy: relationship to long-term glycaemic control

(2008) R. G. Langham et al.   DIABETOLOGIA

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

Simultaneous determination and quantification of seven major phospholipid classes in human blood using normal-phase liquid chromatography coupled with electrospray mass spectrometry and the application in diabetes nephropathy

(2008) L PANG et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Affinity separation and enrichment methods in proteomic analysis

(2008) Xiangming Fang et al.   Journal of Proteomics

IHG-1 Amplifies TGF- 1 Signaling and Is Increased in Renal Fibrosis

(2008) M. Murphy et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

(2008) M. T. Lindenmeyer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Death Ligand TRAIL in Diabetic Nephropathy

(2008) C. Lorz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Urinary Proteomics in Diabetes and CKD

(2008) K. Rossing et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

(2008) P. A. Gonzales et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Decreased glomerular and tubular expression of ACE2 in patients with type 2 diabetes and kidney disease

(2008) Heather N. Reich et al.   KIDNEY INTERNATIONAL

Advanced glycation end-products suppress neuropilin-1 expression in podocytes

(2008) Tzvetanka Bondeva et al.   KIDNEY INTERNATIONAL

Improved Elucidation of Biological Processes Linked to Diabetic Nephropathy by Single Probe-Based Microarray Data Analysis

(2008) Clemens D. Cohen et al.   PLoS One

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

(2007) David W. Walsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE