Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

The Gly(972)Arg Variant of Human IRS1 Gene Is Associated With Variation in Glomerular Filtration Rate Likely Through Impaired Insulin Receptor Signaling

(2012) F. Thameem et al.   DIABETES

Vegfa Protects the Glomerular Microvasculature in Diabetes

(2012) G. A. Sivaskandarajah et al.   DIABETES

AGEs, RAGE, and Diabetic Retinopathy

(2011) Hongliang Zong et al.   Current Diabetes Reports

Podocyte vascular endothelial growth factor (Vegf 164 ) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes

(2011) D. Veron et al.   DIABETOLOGIA

Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells

(2011) Rosemarie M. Carew et al.   FEBS Journal

The BMP-7–Smad1/5/8 Pathway Promotes Kidney Repair After Obstruction Induced Renal Injury

(2011) Scott R. Manson et al.   JOURNAL OF UROLOGY

An intergenic region on chromosome 13q33.3 is associated with the susceptibility to kidney disease in type 1 and 2 diabetes

(2011) Marcus G. Pezzolesi et al.   KIDNEY INTERNATIONAL

Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity

(2011) Akira Mima et al.   KIDNEY INTERNATIONAL

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β?

(2010) Rosemarie M Carew et al.   BMC DEVELOPMENTAL BIOLOGY

Irs1 Serine 307 Promotes Insulin Sensitivity in Mice

(2010) Kyle D. Copps et al.   Cell Metabolism

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Role of the WNK-activated SPAK kinase in regulating blood pressure

(2010) Fatema H. Rafiqi et al.   EMBO Molecular Medicine

Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys

(2010) Jan Willem Leeuwis et al.   JOURNAL OF PATHOLOGY

Glomerular Structure and Function Require Paracrine, Not Autocrine, VEGF-VEGFR-2 Signaling

(2010) K. Sison et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease

(2010) Delma Veron et al.   KIDNEY INTERNATIONAL

Cross Talk between Insulin and Bone Morphogenetic Protein Signaling Systems in Brown Adipogenesis

(2010) H. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Extracellular BMP-antagonist regulation in development and disease: tied up in knots

(2010) David W. Walsh et al.   TRENDS IN CELL BIOLOGY

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

IRS2 variants and syndromes of severe insulin resistance

(2009) W. E. Bottomley et al.   DIABETOLOGIA

Identification of a region in the human IRS2 promoter essential for stress induced transcription depending on SP1, NFI binding and ERK activation in HepG2 cells

(2009) M Udelhoven et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Mouse Models of Diabetic Nephropathy

(2009) F. C. Brosius et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Emerging Genetic Architecture of Type 2 Diabetes

(2008) Alessandro Doria et al.   Cell Metabolism

Podocyte-Derived BMP7 Is Critical for Nephron Development

(2008) I. Kazama et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bone Morphogenetic Protein-7 and Connective Tissue Growth Factor: Novel Targets for Treatment of Renal Fibrosis?

(2008) Tri Q. Nguyen et al.   PHARMACEUTICAL RESEARCH

Interleukin-1β interferes with signal transduction induced by neurotrophin-3 in cortical neurons

(2007) Rungtip Soiampornkul et al.   BRAIN RESEARCH