Suppression of muscle wasting by the plant-derived compound ursolic acid in a model of chronic kidney disease

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

(2016) João-Paulo G. Camporez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of cachexia: An overview of recent developments

(2015) Stephan von Haehling et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation

(2015) H. Peng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Muscle wasting in disease: molecular mechanisms and promising therapies

(2015) Shenhav Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2015

(2015) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

A Simple Protein–Energy Wasting Score Predicts Survival in Maintenance Hemodialysis Patients

(2014) Xavier Moreau-Gaudry et al.   JOURNAL OF RENAL NUTRITION

Mechanisms of muscle wasting in chronic kidney disease

(2014) Xiaonan H. Wang et al.   Nature Reviews Nephrology

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

(2014) Roberta Sartori et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Are we closer to having drugs to treat muscle wasting disease?

(2014) John E. Morley et al.   Journal of Cachexia Sarcopenia and Muscle

Stat3 Activation Links a C/EBPδ to Myostatin Pathway to Stimulate Loss of Muscle Mass

(2013) Liping Zhang et al.   Cell Metabolism

Wasting mechanisms in muscular dystrophy

(2013) Jonghyun Shin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

Why cachexia kills: examining the causality of poor outcomes in wasting conditions

(2013) Kamyar Kalantar-Zadeh et al.   Journal of Cachexia Sarcopenia and Muscle

Ursolic acid directly promotes protein accretion in myotubes but does not affect myoblast proliferation

(2012) Vandré Casagrande Figueiredo et al.   CELL BIOCHEMISTRY AND FUNCTION

Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486

(2012) Jing Xu et al.   KIDNEY INTERNATIONAL

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT

(2012) Rahul Checker et al.   PLoS One

Ursolic Acid Increases Skeletal Muscle and Brown Fat and Decreases Diet-Induced Obesity, Glucose Intolerance and Fatty Liver Disease

(2012) Steven D. Kunkel et al.   PLoS One

mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass

(2011) Steven D. Kunkel et al.   Cell Metabolism

Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease

(2011) Liping Zhang et al.   FASEB JOURNAL

Ursolic Acid Suppresses Interleukin-17 (IL-17) Production by Selectively Antagonizing the Function of RORγt Protein

(2011) Tao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids

(2011) Leslie M. Baehr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Apoptosis and myostatin mRNA are upregulated in the skeletal muscle of patients with chronic kidney disease

(2011) Daniela Verzola et al.   KIDNEY INTERNATIONAL

Cachexia and protein-energy wasting in children with chronic kidney disease

(2011) Robert H. Mak et al.   PEDIATRIC NEPHROLOGY

CCAAT/enhancer binding protein-δ expression is increased in fast skeletal muscle by food deprivation and regulates myostatin transcription in vitro

(2010) David L. Allen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Atrogin-1 Affects Muscle Protein Synthesis and Degradation When Energy Metabolism Is Impaired by the Antidiabetes Drug Berberine

(2010) Huiling Wang et al.   DIABETES

Inflammation and cachexia in chronic kidney disease

(2010) Wai W. Cheung et al.   PEDIATRIC NEPHROLOGY

Comparative functional analysis of the cow and mouse myostatin genes reveals novel regulatory elements in their upstream promoter regions

(2008) David L. Allen et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY