Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis

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AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

(2010) Cédric Artus et al.   EMBO JOURNAL

Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission

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Cytokinesis and cancer: Polo loves ROCK‘n’ Rho(A)

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PICH and Cotargeted Plk1 Coordinately Maintain Prometaphase Chromosome Arm Architecture

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Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

Molecular mechanisms of necroptosis: an ordered cellular explosion

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Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

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Targeted Depletion of Polo-Like Kinase (Plk) 1 Through Lentiviral shRNA or a Small-Molecule Inhibitor Causes Mitotic Catastrophe and Induction of Apoptosis in Human Melanoma Cells

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Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

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Death through a tragedy: mitotic catastrophe

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Polo-like kinase 1 reaches beyond mitosis—cytokinesis, DNA damage response, and development

(2008) Tohru Takaki et al.   CURRENT OPINION IN CELL BIOLOGY

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology