Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

(2016) Bonnie R. Joubert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

(2016) Bonnie R. Joubert et al.   Nature Communications

DNA methylation analysis of Homeobox genes implicatesHOXB7hypomethylation as risk factor for neural tube defects

(2015) Anne Rochtus et al.   Epigenetics

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

(2015) Eilis Hannon et al.   Epigenetics

Nutri-epigenomic Studies Related to Neural Tube Defects: Does Folate Affect Neural Tube Closure Via Changes in DNA Methylation?

(2015) Anne Rochtus et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Sonic Hedgehog Signaling Affected by Promoter Hypermethylation Induces Aberrant Gli2 Expression in Spina Bifida

(2015) Xiao-Lin Lu et al.   MOLECULAR NEUROBIOLOGY

A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain Tissue

(2015) Edwin J. C. G. van den Oord et al.   SCHIZOPHRENIA BULLETIN

Concordant and discordant DNA methylation signatures of aging in human blood and brain

(2015) Pau Farré et al.   Epigenetics & Chromatin

The effects of long-term daily folic acid and vitamin B12 supplementation on genome-wide DNA methylation in elderly subjects

(2015) Dieuwertje E. G. Kok et al.   Clinical Epigenetics

SOX18 Is a Novel Target Gene of Hedgehog Signaling in Cervical Carcinoma Cell Lines

(2015) Isidora Petrovic et al.   PLoS One

Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure

(2014) Jonathan J. Wilde et al.   Annual Review of Genetics

Neural Tube Defects

(2014) Nicholas D.E. Greene et al.   Annual Review of Neuroscience

Joint Testing of Genotypic and Gene-Environment Interaction Identified Novel Association for BMP4 with Non-Syndromic CL/P in an Asian Population Using Data from an International Cleft Consortium

(2014) Qianqian Chen et al.   PLoS One

On the outside, looking in: A review and evaluation of the comparability of blood and brain “-omes”

(2013) Daniel S. Tylee et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia

(2013) Sanja A. Farkas et al.   Epigenetics

Distinctive patterns of DNA methylation associated with Parkinson disease

(2013) Eliezer Masliah et al.   Epigenetics

Altered methylation of IGF2 DMR0 is associated with neural tube defects

(2013) Lihua Wu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Alteration of Fatty-Acid-Metabolizing Enzymes Affects Mitochondrial Form and Function in Hereditary Spastic Paraplegia

(2012) Christelle Tesson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variability in expression of a familial 2.79 Mb microdeletion in chromosome14q22.1-22.2

(2012) Aimé Lumaka et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

(2012) D. Wang et al.   BIOINFORMATICS

Different measures of “genome-wide” DNA methylation exhibit unique properties in placental and somatic tissues

(2012) E. Magda Price et al.   Epigenetics

Association of genomic instability and the methylation status of imprinted genes and mismatch-repair genes, with neural tube defects

(2012) Zhuo Liu et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Embryonic developmental toxicity of selenite in zebrafish (Danio rerio) and prevention with folic acid

(2012) Yan Ma et al.   FOOD AND CHEMICAL TOXICOLOGY

Methylation Defect in Imprinted Genes Detected in Patients with an Albright's Hereditary Osteodystrophy Like Phenotype and Platelet Gs Hypofunction

(2012) Benedetta Izzi et al.   PLoS One

Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

(2012) Nizar Touleimat et al.   Epigenomics

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

The emerging role of epigenetic mechanisms in the etiology of neural tube defects

(2011) Nicholas D.E. Greene et al.   Epigenetics

Altered Methylation of the DNA Repair Gene MGMT Is Associated with Neural Tube Defects

(2011) Susanna Tran et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Evaluation of the Infinium Methylation 450K technology

(2011) Sarah Dedeurwaerder et al.   Epigenomics

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

(2011) Jason Gertz et al.   PLoS Genetics

Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

(2010) Li Wang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epigenetic control of Hox genes during neurogenesis, development, and disease

(2010) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

A new approach to imprinting mutation detection in GNAS by Sequenom EpiTYPER system

(2010) Benedetta Izzi et al.   CLINICA CHIMICA ACTA

Epidemiologic and genetic aspects of spina bifida and other neural tube defects

(2010) Kit Sing Au et al.   Developmental Disabilities Research Reviews

Folic acid, methylation and neural tube closure in humans

(2009) Henk J. Blom   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Genetics of human neural tube defects

(2009) N. D.E. Greene et al.   HUMAN MOLECULAR GENETICS

Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways

(2008) Preeti Bakrania et al.   AMERICAN JOURNAL OF HUMAN GENETICS