Concordant and discordant DNA methylation signatures of aging in human blood and brain

oxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips

(2015) Sabrina K. Stewart et al.   METHODS

Statistical significance of variables driving systematic variation in high-dimensional data

(2014) Neo Christopher Chung et al.   BIOINFORMATICS

A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control

(2014) Yinming Jiao et al.   BIOINFORMATICS

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

Epigenome-wide association studies without the need for cell-type composition

(2014) James Zou et al.   NATURE METHODS

Short-term diesel exhaust inhalation in a controlled human crossover study is associated with changes in DNA methylation of circulating mononuclear cells in asthmatics

(2014) Ruiwei Jiang et al.   Particle and Fibre Toxicology

Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder

(2014) Esther R. Berko et al.   PLoS Genetics

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

(2014) Nicholas E. Banovich et al.   PLoS Genetics

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

(2014) Carola Weidner et al.   GENOME BIOLOGY

Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain

(2014) Lu Wen et al.   GENOME BIOLOGY

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

(2014) Andrew E Jaffe et al.   GENOME BIOLOGY

Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming

(2013) Chun-Xiao Song et al.   CELL

DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery

(2013) Markus Ahrens et al.   Cell Metabolism

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

(2013) Robert Lowe et al.   Epigenetics

A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression

(2013) Jerry Guintivano et al.   Epigenetics

Blood-based profiles of DNA methylation predict the underlying distribution of cell types

(2013) Devin C Koestler et al.   Epigenetics

Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

(2013) A. E. Teschendorff et al.   HUMAN MOLECULAR GENETICS

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects

(2013) Joseph L. McClay et al.   HUMAN MOLECULAR GENETICS

Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites

(2013) I. Florath et al.   HUMAN MOLECULAR GENETICS

Common DNA methylation alterations in multiple brain regions in autism

(2013) C Ladd-Acosta et al.   MOLECULAR PSYCHIATRY

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

(2013) Åsa Johansson et al.   PLoS One

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

(2013) Roderick C Slieker et al.   Epigenetics & Chromatin

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

Commentary: The seven plagues of epigenetic epidemiology

(2012) Bastiaan T Heijmans et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Factors underlying variable DNA methylation in a human community cohort

(2012) L. L. Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

(2012) M. J. Booth et al.   SCIENCE

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

(2012) Matthew N Davies et al.   GENOME BIOLOGY

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Genomic mapping of 5-hydroxymethylcytosine in the human brain

(2011) Seung-Gi Jin et al.   NUCLEIC ACIDS RESEARCH

Extensive epigenetic reprogramming in human somatic tissues between fetus and adult

(2011) Ryan KC Yuen et al.   Epigenetics & Chromatin

Evaluation of the Infinium Methylation 450K technology

(2011) Sarah Dedeurwaerder et al.   Epigenomics

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

Familial Aggregation of Suicide Explained by Cluster B Traits: A Three-Group Family Study of Suicide Controlling for Major Depressive Disorder

(2009) Alexander McGirr et al.   AMERICAN JOURNAL OF PSYCHIATRY

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

The Relationship of DNA Methylation with Age, Gender and Genotype in Twins and Healthy Controls

(2009) Marco P. Boks et al.   PLoS One

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

(2009) Adolfo Sequeira et al.   PLoS One

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

(2009) Brock C. Christensen et al.   PLoS Genetics

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH