Sonic Hedgehog Signaling Affected by Promoter Hypermethylation Induces Aberrant Gli2 Expression in Spina Bifida

Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells

(2014) Mehdi Hayat Shahi et al.   PLoS One

Non-canonical functions of the DNA methylome in gene regulation

(2013) James P. Reddington et al.   BIOCHEMICAL JOURNAL

Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord

(2013) K. Yu et al.   DEVELOPMENT

Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia

(2013) Sanja A. Farkas et al.   Epigenetics

Altered methylation of IGF2 DMR0 is associated with neural tube defects

(2013) Lihua Wu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

(2013) J. B. Wallingford et al.   SCIENCE

Anorectal atresia and Variants at Predicted Regulatory Sites in Candidate Genes

(2012) Tonia C. Carter et al.   ANNALS OF HUMAN GENETICS

Neural tube defects and maternal intake of micronutrients related to one-carbon metabolism or antioxidant activity

(2012) Angela L. Chandler et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Molecular genetic control of cell patterning and fate determination in the developing ventral spinal cord

(2012) Michael P. Matise   Wiley Interdisciplinary Reviews-Developmental Biology

Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo

(2011) Juan Li et al.   DEVELOPMENTAL DYNAMICS

Chromatin landscape

(2011) Joshua C. Black et al.   Epigenetics

The emerging role of epigenetic mechanisms in the etiology of neural tube defects

(2011) Nicholas D.E. Greene et al.   Epigenetics

Role of GLI2 in the growth of human osteosarcoma

(2011) Hiroko Nagao et al.   JOURNAL OF PATHOLOGY

Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

(2010) Li Wang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

(2010) Jennifer N. Murdoch et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

(2010) Mehdi H Shahi et al.   BMC CANCER

Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels

(2010) Kazuto Sugimura et al.   EXPERIMENTAL CELL RESEARCH

Insights into metabolic mechanisms underlying folate-responsive neural tube defects: A minireview

(2009) Anna E. Beaudin et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects

(2009) Anne M. Molloy et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Genetics of human neural tube defects

(2009) N. D.E. Greene et al.   HUMAN MOLECULAR GENETICS

One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies

(2009) Patrick J. Stover   JOURNAL OF NUTRITION

DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences

(2009) S. J. Diede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding and exploitinghTERTpromoter regulation for diagnosis and treatment of human cancers

(2008) Satoru Kyo et al.   CANCER SCIENCE

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

(2008) Yong Pan et al.   DEVELOPMENTAL BIOLOGY