Modulation of Bcl-x Alternative Splicing Induces Apoptosis of Human Hepatic Stellate Cells

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Fibrosis Progression in Nonalcoholic Fatty Liver vs Nonalcoholic Steatohepatitis: A Systematic Review and Meta-analysis of Paired-Biopsy Studies

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Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies

(2013) Don C. Rockey   Clinical Gastroenterology and Hepatology

Hepatic stellate cells in liver development, regeneration, and cancer

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Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Clearance of activated stellate cells for hepatic fibrosis regression: Molecular basis and translational potential

(2012) Desong Kong et al.   BIOMEDICINE & PHARMACOTHERAPY

Drug targeting to the diseased liver

(2012) Klaas Poelstra et al.   JOURNAL OF CONTROLLED RELEASE

Endoplasmic Reticulum stress induces hepatic stellate cell apoptosis and contributes to fibrosis resolution

(2012) Samuele De Minicis et al.   LIVER INTERNATIONAL

Navitoclax (ABT-263) Reduces Bcl-xL-Mediated Chemoresistance in Ovarian Cancer Models

(2012) M. Wong et al.   MOLECULAR CANCER THERAPEUTICS

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

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Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis

(2011) Xin Ming   Expert Opinion on Drug Delivery

Exon skipping and dystrophin restoration in patients with Duchenne muscular dystrophy after systemic phosphorodiamidate morpholino oligomer treatment: an open-label, phase 2, dose-escalation study

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Antitumorigenic potential of STAT3 alternative splicing modulation

(2011) F. Zammarchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current status of novel antifibrotic therapies in patients with chronic liver disease

(2011) Michal Cohen-Naftaly et al.   Therapeutic Advances in Gastroenterology

Induction of matrix metalloproteinase-1 gene transcription by tumour necrosis factor α via the p50/p50 homodimer of nuclear factor-κ B in activated human hepatic stellate cells

(2010) Shigenari Hozawa et al.   LIVER INTERNATIONAL

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Anti-tumor activity of splice-switching oligonucleotides

(2010) John A. Bauman et al.   NUCLEIC ACIDS RESEARCH

Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells

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Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection

(2009) S. A. Gonzalez et al.   JOURNAL OF VIRAL HEPATITIS

Fibrosis and Cirrhosis Reversibility – Molecular Mechanisms

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The Global Impact of Hepatic Fibrosis and End-Stage Liver Disease

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The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells

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Pharmacokinetics and Biodistribution of Nanoparticles

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The BCL-2 protein family: opposing activities that mediate cell death

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