Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice

(2015) Fahad A. Somaa et al.   EXPERIMENTAL NEUROLOGY

Optogenetics enables functional analysis of human embryonic stem cell–derived grafts in a Parkinson's disease model

(2015) Julius A Steinbeck et al.   NATURE BIOTECHNOLOGY

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

(2015) Chris R. Bye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human pluripotent stem cell derived midbrain PITX3eGFP/w neurons: a versatile tool for pharmacological screening and neurodegenerative modeling

(2015) Bradley Watmuff et al.   Frontiers in Cellular Neuroscience

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

(2014) Shane Grealish et al.   Cell Stem Cell

Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation

(2014) Daisuke Doi et al.   Stem Cell Reports

Improved Cell Therapy Protocols for Parkinson's Disease Based on Differentiation Efficiency and Safety of hESC-, hiPSC-, and Non-Human Primate iPSC-Derived Dopaminergic Neurons

(2013) Maria Sundberg et al.   STEM CELLS

Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines

(2013) Jonathan C. Niclis et al.   Frontiers in Cellular Neuroscience

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

(2012) A. D. Carri et al.   DEVELOPMENT

Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into Parkinsonian mice

(2012) Christopher R. Bye et al.   EXPERIMENTAL NEUROLOGY

Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice

(2012) Jessica Kauhausen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

(2012) Roger A Barker et al.   LANCET NEUROLOGY

Glycogen Synthase Kinase 3β and Activin/Nodal Inhibition in Human Embryonic Stem Cells Induces a Pre-Neuroepithelial State That Is Required for Specification to a Floor Plate Cell Lineage

(2012) Mark Denham et al.   STEM CELLS

Specification of Midbrain Dopamine Neurons from Primate Pluripotent Stem Cells

(2012) Jiajie Xi et al.   STEM CELLS

Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC-Derived Neural Cells in a Primate Model of Parkinson's Disease

(2012) Daisuke Doi et al.   STEM CELLS

Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

(2012) Agnete Kirkeby et al.   Cell Reports

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture

(2011) Heidi Hongisto et al.   Stem Cell Research

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

(2008) Clare L. Parish et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of the Factors that Limit the Ability of Feeder Cells to Maintain the Undifferentiated State of Human Embryonic Stem Cells

(2008) Luis G. Villa-Diaz et al.   STEM CELLS AND DEVELOPMENT