Specification of Midbrain Dopamine Neurons from Primate Pluripotent Stem Cells

Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice

(2012) Lixiang Ma et al.   Cell Stem Cell

Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain

(2012) L. Lahti et al.   DEVELOPMENT

Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells

(2011) I. Jaeger et al.   DEVELOPMENT

Efficient Generation of A9 Midbrain Dopaminergic Neurons by Lentiviral Delivery of LMX1A in Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

(2011) A. Sánchez-Danés et al.   HUMAN GENE THERAPY

Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells

(2010) Christopher A. Fasano et al.   Cell Stem Cell

A simple method for large-scale generation of dopamine neurons from human embryonic stem cells

(2010) Asuka Morizane et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid

(2010) Oliver Cooper et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

(2010) B.-Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

(2010) G. Hargus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

(2010) Mark Denham et al.   STEM CELLS

Wnt1-lmx1a Forms a Novel Autoregulatory Loop and Controls Midbrain Dopaminergic Differentiation Synergistically with the SHH-FoxA2 Pathway

(2009) Sangmi Chung et al.   Cell Stem Cell

Fgf8b-containing spliceforms, but not Fgf8a, are essential for Fgf8 function during development of the midbrain and cerebellum

(2009) Qiuxia Guo et al.   DEVELOPMENTAL BIOLOGY

Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon

(2009) Tomoya Nakatani et al.   DEVELOPMENTAL BIOLOGY

Organization of the human embryonic ventral mesencephalon

(2009) Jenny Nelander et al.   GENE EXPRESSION PATTERNS

Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

(2009) J. N. Guzman et al.   JOURNAL OF NEUROSCIENCE

Shh dependent and independent maintenance of basal midbrain

(2009) Ariadna Perez-Balaguer et al.   MECHANISMS OF DEVELOPMENT

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

(2009) Milan Joksimovic et al.   NATURE NEUROSCIENCE

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

The Role of Lmx1a in the Differentiation of Human Embryonic Stem Cells into Midbrain Dopamine Neurons in Culture and After Transplantation into a Parkinson's Disease Model

(2008) Jingli Cai et al.   STEM CELLS

Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats

(2007) Dali Yang et al.   STEM CELLS