An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

Transcriptome analysis highlights the conserved difference between embryonic and postnatal-derived alveolar macrophages

(2015) S. L. Gibbings et al.   BLOOD

Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia

(2015) Patrick Ejlerskov et al.   CELL

Visualizing real-time influenza virus infection, transmission and protection in ferrets

(2015) Erik A. Karlsson et al.   Nature Communications

Mucosal Immune Responses Predict Clinical Outcomes during Influenza Infection Independently of Age and Viral Load

(2014) Christine M. Oshansky et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endotoxin-induced lung alveolar cell injury causes brain cell damage

(2014) Raquel Rodríguez-González et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

The epithelium in idiopathic pulmonary fibrosis: breaking the barrier

(2014) Ana Camelo et al.   Frontiers in Pharmacology

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Viral infection of the lung: Host response and sequelae

(2013) Jae-Kwang Yoo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Highly Sensitive Real-Time In Vivo Imaging of an Influenza Reporter Virus Reveals Dynamics of Replication and Spread

(2013) V. Tran et al.   JOURNAL OF VIROLOGY

Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases

(2013) Benjamin J Cowling et al.   LANCET

Pathogenesis of influenza-induced acute respiratory distress syndrome

(2013) Kirsty R Short et al.   LANCET INFECTIOUS DISEASES

Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

(2013) L. E. Gralinski et al.   mBio

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

(2013) Amber M. Smith et al.   PLoS Pathogens

Human airway epithelial cell innate immunity: relevance to asthma

(2012) Jeremy A Hirota et al.   CURRENT OPINION IN IMMUNOLOGY

Epithelial cells utilize cortical actin/myosin to activate latent TGF-β through integrin αvβ6-dependent physical force

(2012) Marilyn M. Giacomini et al.   EXPERIMENTAL CELL RESEARCH

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells

(2012) Kotaro Sugimoto et al.   JOURNAL OF CLINICAL INVESTIGATION

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Macrophage Subpopulations Characterize Acute Infection and Chronic Inflammatory Lung Disease

(2012) M. Duan et al.   JOURNAL OF IMMUNOLOGY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

An Official American Thoracic Society Workshop Report: Features and Measurements of Experimental Acute Lung Injury in Animals

(2011) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impaired Wound Healing Predisposes Obese Mice to Severe Influenza Virus Infection

(2011) Kevin B. O’Brien et al.   JOURNAL OF INFECTIOUS DISEASES

Increased Pathogenicity of a Reassortant 2009 Pandemic H1N1 Influenza Virus Containing an H5N1 Hemagglutinin

(2011) T. D. Cline et al.   JOURNAL OF VIROLOGY

Phenotypes and functions of persistent Sendai virus-induced antibody forming cells and CD8+ T cells in diffuse nasal-associated lymphoid tissue typify lymphocyte responses of the gut

(2011) Rajeev Rudraraju et al.   VIROLOGY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Foot-and-Mouth Disease Virus Replicates Only Transiently in Well-Differentiated Porcine Nasal Epithelial Cells

(2010) P. Dash et al.   JOURNAL OF VIROLOGY

Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis

(2010) Christina M. Carlson et al.   PLoS Pathogens

β6 Integrin Subunit Deficiency Alleviates Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

(2009) Anna Hogmalm et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone

(2008) Minmin Ma et al.   BMC NEUROSCIENCE

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

(2008) J. C. Chase et al.   INFECTION AND IMMUNITY