Cytoplasmic Viral RNA-Dependent RNA Polymerase Disrupts the Intracellular Splicing Machinery by Entering the Nucleus and Interfering with Prp8

Crystal structure of Prp8 reveals active site cavity of the spliceosome

(2013) Wojciech P. Galej et al.   NATURE

Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly

(2013) Xueni Li et al.   NUCLEIC ACIDS RESEARCH

Cambodia unravels cause of mystery illness

(2012) Abby Seiff   LANCET

Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease

(2011) Enrique Álvarez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enterovirus-Induced miR-141 Contributes to Shutoff of Host Protein Translation by Targeting the Translation Initiation Factor eIF4E

(2011) Bing-Ching Ho et al.   Cell Host & Microbe

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

(2010) Kuo-Ming Lee et al.   NUCLEIC ACIDS RESEARCH

The spliceosomal proteome: At the heart of the largest cellular ribonucleoprotein machine

(2010) Saba Valadkhan et al.   PROTEOMICS

Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China

(2010) Yang Wu et al.   Protein & Cell

Novel Antiviral Agent DTriP-22 Targets RNA-Dependent RNA Polymerase of Enterovirus 71

(2009) T.-C. Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Splicing of mRNA precursors: the role of RNAs and proteins in catalysis

(2009) Chaim Wachtel et al.   Molecular BioSystems

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Appearance of mosaic enterovirus 71 in the 2008 outbreak of China

(2009) Nai-Zheng Ding et al.   VIRUS RESEARCH

Enterovirus 71 3C Protease Cleaves a Novel Target CstF-64 and Inhibits Cellular Polyadenylation

(2009) Kuo-Feng Weng et al.   PLoS Pathogens

Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases

(2008) G. Campagnola et al.   JOURNAL OF VIROLOGY

Divergent picornavirus IRES elements

(2008) Graham J. Belsham   VIRUS RESEARCH