A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

Supportive Care of the First 2 Ebola Virus Disease Patients at the Monrovia Medical Unit

(2015) Karen K. Wong et al.   CLINICAL INFECTIOUS DISEASES

Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications

(2015) Rodrigo Jácome et al.   PLoS One

A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity

(2015) Lisa M. Johansen et al.   Science Translational Medicine

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

(2014) Lisa Oestereich et al.   ANTIVIRAL RESEARCH

Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

(2014) Wei Xu et al.   Cell Host & Microbe

Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses

(2014) Diana F Florescu et al.   Expert Review of Anti-Infective Therapy

Reverse genetics systems as tools for the development of novel therapies against filoviruses

(2014) Thomas Hoenen et al.   Expert Review of Anti-Infective Therapy

A Novel Life Cycle Modeling System for Ebola Virus Shows a Genome Length-Dependent Role of VP24 in Virus Infectivity

(2014) A. Watt et al.   JOURNAL OF VIROLOGY

Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial

(2014) Jared M Baeten et al.   LANCET INFECTIOUS DISEASES

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430

(2014) Travis K. Warren et al.   NATURE

Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

(2014) Gary Wong et al.   VACCINE

Essential Role for the Mnk Pathway in the Inhibitory Effects of Type I Interferons on Myeloproliferative Neoplasm (MPN) Precursors

(2013) Swarna Mehrotra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monoclonal Antibodies Combined with Adenovirus-Vectored Interferon Significantly Extend the Treatment Window in Ebola Virus-Infected Guinea Pigs

(2013) X. Qiu et al.   JOURNAL OF VIROLOGY

FDA-Approved Selective Estrogen Receptor Modulators Inhibit Ebola Virus Infection

(2013) L. M. Johansen et al.   Science Translational Medicine

A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine

(2012) Nittaya Phanuphak et al.   ANTIVIRAL THERAPY

Interferon-β Therapy Prolongs Survival in Rhesus Macaque Models of Ebola and Marburg Hemorrhagic Fever

(2012) Lauren M. Smith et al.   JOURNAL OF INFECTIOUS DISEASES

Ebolavirus Proteins Suppress the Effects of Small Interfering RNA by Direct Interaction with the Mammalian RNA Interference Pathway

(2011) G. Fabozzi et al.   JOURNAL OF VIROLOGY

Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription

(2010) T. Hoenen et al.   VIROLOGY

Evasion of the Interferon-Mediated Antiviral Response by Filoviruses

(2010) Washington B. Cárdenas   Viruses-Basel

Antiretroviral Tissue Kinetics: In Vivo Imaging Using Positron Emission Tomography

(2009) M. Di Mascio et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens