A Novel Life Cycle Modeling System for Ebola Virus Shows a Genome Length-Dependent Role of VP24 in Virus Infectivity

A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals

(2013) Thomas Hoenen et al.   ANTIVIRAL RESEARCH

Role of the Phosphatidylserine Receptor TIM-1 in Enveloped-Virus Entry

(2013) S. Moller-Tank et al.   JOURNAL OF VIROLOGY

Arenavirus Budding: A Common Pathway with Mechanistic Differences

(2013) Svenja Wolff et al.   Viruses-Basel

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

(2013) Reed S. Shabman et al.   PLoS Pathogens

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Inclusion Bodies Are a Site of Ebolavirus Replication

(2012) T. Hoenen et al.   JOURNAL OF VIROLOGY

The Organisation of Ebola Virus Reveals a Capacity for Extensive, Modular Polyploidy

(2012) Daniel R. Beniac et al.   PLoS One

Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography

(2012) T. A. M. Bharat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cathepsin B & L Are Not Required for Ebola Virus Replication

(2012) Andrea Marzi et al.   PLoS Neglected Tropical Diseases

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

(2012) Adrianna P. P. Zhang et al.   PLoS Pathogens

Minigenomes, transcription and replication competent virus-like particles and beyond: Reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses

(2011) Thomas Hoenen et al.   ANTIVIRAL RESEARCH

Genus-specific recruitment of filovirus ribonucleoprotein complexes into budding particles

(2011) L. Spiegelberg et al.   JOURNAL OF GENERAL VIROLOGY

Ebola Virus Enters Host Cells by Macropinocytosis and Clathrin-Mediated Endocytosis

(2011) Paulina Aleksandrowicz et al.   JOURNAL OF INFECTIOUS DISEASES

The Ebolavirus VP24 Protein Blocks Phosphorylation of p38 Mitogen-Activated Protein Kinase

(2011) Peter Halfmann et al.   JOURNAL OF INFECTIOUS DISEASES

Knockdown of Ebola Virus VP24 Impairs Viral Nucleocapsid Assembly and Prevents Virus Replication

(2011) Mathieu Mateo et al.   JOURNAL OF INFECTIOUS DISEASES

The Ebola Virus VP24 Protein Prevents hnRNP C1/C2 Binding to Karyopherin α1 and Partially Alters its Nuclear Import

(2011) Reed S. Shabman et al.   JOURNAL OF INFECTIOUS DISEASES

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

(2011) A. S. Kondratowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishment and application of an infectious virus-like particle system for Marburg virus

(2010) J. Wenigenrath et al.   JOURNAL OF GENERAL VIROLOGY

Oligomerization of Ebola Virus VP40 Is Essential for Particle Morphogenesis and Regulation of Viral Transcription

(2010) T. Hoenen et al.   JOURNAL OF VIROLOGY

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription

(2010) T. Hoenen et al.   VIROLOGY

Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes

(2010) Mohammad F. Saeed et al.   PLoS Pathogens

Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner

(2010) Asuka Nanbo et al.   PLoS Pathogens

The RING Domain and the L79 Residue of Z Protein Are Involved in both the Rescue of Nucleocapsids and the Incorporation of Glycoproteins into Infectious Chimeric Arenavirus-Like Particles

(2009) J. C. Casabona et al.   JOURNAL OF VIROLOGY

Ebolavirus VP24 Binding to Karyopherins Is Required for Inhibition of Interferon Signaling

(2009) M. Mateo et al.   JOURNAL OF VIROLOGY

Generation of biologically contained Ebola viruses

(2008) P. Halfmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA