Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses

Selection and Recombinant Phenotyping of a Novel CMX001 and Cidofovir Resistance Mutation in Human Cytomegalovirus

(2013) Scott H. James et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dynamics of cytomegalovirus populations harbouring mutations in genes UL54 and UL97 in a haematopoietic stem cell transplant recipient

(2013) Nathalie Schnepf et al.   JOURNAL OF CLINICAL VIROLOGY

CMX001 to Prevent Cytomegalovirus Disease in Hematopoietic-Cell Transplantation

(2013) Francisco M. Marty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emergence of Cowpox: Study of the Virulence of Clinical Strains and Evaluation of Antivirals

(2013) Sophie Duraffour et al.   PLoS One

First Pharmacokinetic and Safety Study in Humans of the Novel Lipid Antiviral Conjugate CMX001, a Broad-Spectrum Oral Drug Active against Double-Stranded DNA Viruses

(2012) Wendy Painter et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox – An animal model of smallpox

(2012) Scott Parker et al.   ANTIVIRAL RESEARCH

Detection of Molluscum Contagiosum Virus (MCV) DNA in the Plasma of an Immunocompromised Patient and Possible Reduction of MCV DNA With CMX-001

(2012) Jeffrey I. Cohen et al.   JOURNAL OF INFECTIOUS DISEASES

Progressive Vaccinia: Case Description and Laboratory-Guided Therapy With Vaccinia Immune Globulin, ST-246, and CMX001

(2012) E. R. Lederman et al.   JOURNAL OF INFECTIOUS DISEASES

CMX001 (1-O-Hexadecyloxypropyl-Cidofovir) Inhibits Polyomavirus JC Replication in Human Brain Progenitor-Derived Astrocytes

(2011) Rainer Gosert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Safety and Efficacy of CMX001 as Salvage Therapy for Severe Adenovirus Infections in Immunocompromised Patients

(2011) Diana F. Florescu et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Risk Factors for Systemic Candida Infections in Pediatric Small Bowel Transplant Recipients

(2011) Diana F. Florescu et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

The eradication of smallpox – An overview of the past, present, and future

(2011) Donald A. Henderson   VACCINE

Efficacy of CMX001 as a Prophylactic and Presymptomatic Antiviral Agent in New Zealand White Rabbits Infected with Rabbitpox Virus, a Model for Orthopoxvirus Infections of Humans

(2011) Amanda D. Rice et al.   Viruses-Basel

Oral Hexadecyloxypropyl-Cidofovir Therapy in Pregnant Guinea Pigs Improves Outcome in the Congenital Model of Cytomegalovirus Infection

(2010) Fernando J. Bravo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

1-O-Hexadecyloxypropyl Cidofovir (CMX001) Effectively Inhibits Polyomavirus BK Replication in Primary Human Renal Tubular Epithelial Cells

(2010) C. H. Rinaldo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hexadecyloxypropyl-Cidofovir (CMX001) Suppresses JC Virus Replication in Human Fetal Brain SVG Cell Cultures

(2010) Z.-G. Jiang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A case of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia

(2010) A. Patel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies

(2010) Debra C. Quenelle et al.   JOURNAL OF INFECTIOUS DISEASES

Development of CMX001 for the Treatment of Poxvirus Infections

(2010) Randall Lanier et al.   Viruses-Basel

Synthesis and Early Development of Hexadecyloxypropyl-cidofovir: An Oral Antipoxvirus Nucleoside Phosphonate

(2010) Karl Y. Hostetler   Viruses-Basel

Ectromelia Virus Infections of Mice as a Model to Support the Licensure of Anti-Orthopoxvirus Therapeutics

(2010) Scott Parker et al.   Viruses-Basel

Treatment of Vaccinia and Cowpox Virus Infections in Mice with CMX001 and ST-246

(2010) Debra C. Quenelle et al.   Viruses-Basel

Cidofovir Inhibits Polyomavirus BK Replication in Human Renal Tubular Cells Downstream of Viral Early Gene Expression

(2008) E. Bernhoff et al.   AMERICAN JOURNAL OF TRANSPLANTATION