Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems

Use of ‘dilute-and-shoot’ liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma

(2016) Simone Esposito et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

The metabolic control of schistosome egg production

(2015) Edward J. Pearce et al.   CELLULAR MICROBIOLOGY

Repurposing of anticancer drugs: in vitro and in vivo activities against Schistosoma mansoni

(2015) Noemi Cowan et al.   Parasites & Vectors

Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni

(2015) Cristiana Lalli et al.   PLoS Neglected Tropical Diseases

Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails

(2014) Flávia FB Couto et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Schistosomiasis control: praziquantel forever?

(2014) Donato Cioli et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Serum albumin and α-1 acid glycoprotein impede the killing of Schistosoma mansoni by the tyrosine kinase inhibitor Imatinib

(2014) Svenja Beckmann et al.   International Journal for Parasitology-Drugs and Drug Resistance

Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug

(2014) Ibrahim N. Mwangi et al.   International Journal for Parasitology-Drugs and Drug Resistance

Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs

(2014) Steffen Hahnel et al.   Frontiers in Genetics

Disposition of Mefloquine and Enpiroline Is Highly Influenced by a Chronic Schistosoma mansoni Infection

(2013) Katrin Ingram et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Study of Transcriptome Profiles of Mechanical- and Skin-Transformed Schistosoma mansoni Schistosomula

(2013) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

Discovery of Anthelmintic Drug Targets and Drugs Using Chokepoints in Nematode Metabolic Pathways

(2013) Christina M. Taylor et al.   PLoS Pathogens

Cell Death and Reproductive Regression in Female Schistosoma mansoni

(2012) Sarah E. Galanti et al.   PLoS Neglected Tropical Diseases

Fatty Acid Oxidation Is Essential for Egg Production by the Parasitic Flatworm Schistosoma mansoni

(2012) Stanley Ching-Cheng Huang et al.   PLoS Pathogens

Metabolic Modulator Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy

(2010) Khalid Abozguia et al.   CIRCULATION

Something worth dyeing for: Molecular tools for the dissection of lipid metabolism inCaenorhabditis elegans

(2010) Ida Coordt Elle et al.   FEBS LETTERS

Schistosoma mansoni: signal transduction processes during the development of the reproductive organs

(2010) S. BECKMANN et al.   PARASITOLOGY

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

(2010) Emily Peak et al.   PLoS Neglected Tropical Diseases

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

(2009) Kelvin Yen et al.   AGE

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

(2009) Sandra D. Melman et al.   PLoS Neglected Tropical Diseases

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Response of Schistosoma mansoni Isolates Having Different Drug Sensitivity to Praziquantel Over Several Life Cycle Passages with and Without Therapeutic Pressure

(2008) Abdel Nasser A. Sabra et al.   JOURNAL OF PARASITOLOGY