Discovery of Anthelmintic Drug Targets and Drugs Using Chokepoints in Nematode Metabolic Pathways

Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors

(2012) Claude L. Charvet et al.   INVERTEBRATE NEUROSCIENCE

Fatty Acid Oxidation Is Essential for Egg Production by the Parasitic Flatworm Schistosoma mansoni

(2012) Stanley Ching-Cheng Huang et al.   PLoS Pathogens

Identification of Pyruvate Kinase in Methicillin-Resistant Staphylococcus aureus as a Novel Antimicrobial Drug Target

(2011) Roya Zoraghi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Reliability analysis of the Ahringer Caenorhabditis elegans RNAi feeding library: a guide for genome-wide screens

(2011) Wubin Qu et al.   BMC GENOMICS

Pyrimidine Salvage Pathway in Mycobacterium tuberculosis

(2011) A. D. Villela et al.   CURRENT MEDICINAL CHEMISTRY

The draft genome of the parasitic nematode Trichinella spiralis

(2011) Makedonka Mitreva et al.   NATURE GENETICS

Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data

(2011) J. Martin et al.   NUCLEIC ACIDS RESEARCH

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Managing Nematodes Without Methyl Bromide

(2010) Inga A. Zasada et al.   Annual Review of Phytopathology

Mitochondrial Dysfunction Confers Resistance to Multiple Drugs in Caenorhabditis elegans

(2010) Iryna O. Zubovych et al.   MOLECULAR BIOLOGY OF THE CELL

A new bioinformatics analysis tools framework at EMBL-EBI

(2010) M. Goujon et al.   NUCLEIC ACIDS RESEARCH

Trichomonas vaginalis nucleoside triphosphate diphosphohydrolase and ecto-5′-nucleotidase activities are inhibited by lycorine and candimine

(2010) Raquel B. Giordani et al.   PARASITOLOGY INTERNATIONAL

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

‘Load Points’ and ‘Choke Points’ as Nodes for Prioritizing Drug Targets in Pseudomonas aeruginosa (Supplementary)

(2009) Deepak Perumal et al.   Current Bioinformatics

Pharmacotherapy of helminth infection

(2009) Erwin van den Enden   EXPERT OPINION ON PHARMACOTHERAPY

Massively parallel sequencing of the polyadenylated transcriptome of C. elegans

(2009) L. W. Hillier et al.   GENOME RESEARCH

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Metabolite-centric approaches for the discovery of antibacterials using genome-scale metabolic networks

(2009) Tae Yong Kim et al.   METABOLIC ENGINEERING

The genome of the blood fluke Schistosoma mansoni

(2009) Matthew Berriman et al.   NATURE

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

WormBase: a comprehensive resource for nematode research

(2009) Todd W. Harris et al.   NUCLEIC ACIDS RESEARCH

Helminth Genomics: The Implications for Human Health

(2009) Paul J. Brindley et al.   PLoS Neglected Tropical Diseases

Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico

(2008) Segun Fatumo et al.   INFECTION GENETICS AND EVOLUTION

Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice

(2008) Lucia Kucerova et al.   JOURNAL OF GENE MEDICINE

Possible Effects of Microbial Ecto-Nucleoside Triphosphate Diphosphohydrolases on Host-Pathogen Interactions

(2008) F. M. Sansom et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

(2008) Pierre Abad et al.   NATURE BIOTECHNOLOGY

The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism

(2008) Christoph Dieterich et al.   NATURE GENETICS

The art and design of genetic screens: RNA interference

(2008) Michael Boutros et al.   NATURE REVIEWS GENETICS

Sequence and genetic map of Meloidogyne hapla: A compact nematode genome for plant parasitism

(2008) C. H. Opperman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Impact of Repeated Rounds of Mass Drug Administration with Diethylcarbamazine Plus Albendazole on Bancroftian Filariasis in Papua New Guinea

(2008) Gary J. Weil et al.   PLoS Neglected Tropical Diseases