Yeast-Based High-Throughput Screens to Identify Novel Compounds Active against Brugia malayi

Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases

(2015) K. Williams et al.   Journal of the Royal Society Interface

Systematic humanization of yeast genes reveals conserved functions and genetic modularity

(2015) A. H. Kachroo et al.   SCIENCE

Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis

(2015) Christina A. Bulman et al.   PLoS Neglected Tropical Diseases

grofit: Fitting Biological Growth Curves withR

(2015) Matthias Kahm et al.   Journal of Statistical Software

The long N-terminus of the C. elegans DNA repair enzyme APN-1 targets the protein to the nucleus of a heterologous system

(2014) Zhiqiang Wang et al.   GENE

Functional Coupling of a Nematode Chemoreceptor to the Yeast Pheromone Response Pathway

(2014) Muhammad Tehseen et al.   PLoS One

A Target Repurposing Approach Identifies N-myristoyltransferase as a New Candidate Drug Target in Filarial Nematodes

(2014) Brendan D. Galvin et al.   PLoS Neglected Tropical Diseases

Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

(2013) E. Bilsland et al.   Open Biology

Immunopathogenesis of lymphatic filarial disease

(2012) Subash Babu et al.   Seminars in Immunopathology

A new approach for anthelmintic discovery for humans

(2012) Timothy G. Geary et al.   TRENDS IN PARASITOLOGY

WormAssay: A Novel Computer Application for Whole-Plate Motion-based Screening of Macroscopic Parasites

(2012) Chris Marcellino et al.   PLoS Neglected Tropical Diseases

Functional expression and characterization of the C. elegans G-protein-coupled FLP-2 Receptor (T19F4.1) in mammalian cells and yeast

(2012) Martha J. Larsen et al.   International Journal for Parasitology-Drugs and Drug Resistance

ABC transporters influence sensitivity of Brugia malayi to moxidectin and have potential roles in drug resistance

(2011) L.E. Stitt et al.   EXPERIMENTAL PARASITOLOGY

Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast

(2011) Elizabeth Bilsland et al.   PLoS Neglected Tropical Diseases

Assay Strategies for the Discovery and Validation of Therapeutics Targeting Brugia pahangi Hsp90

(2010) Tony Taldone et al.   PLoS Neglected Tropical Diseases