Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

Novartis Malaria Initiative: best practice example of pharmaceutical industry's engagement in the fight against malaria

(2011) Gilbert Lefèvre et al.   Annals of the New York Academy of Sciences

Drugs for Neglected Diseasesinitiativemodel of drug development for neglected diseases: current status and future challenges

(2011) Jean-Robert Ioset et al.   Future Medicinal Chemistry

Drug Developers Finally Take Aim at a Neglected Disease

(2011) M. Leslie   SCIENCE

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast

(2011) Elizabeth Bilsland et al.   PLoS Neglected Tropical Diseases

When pharmaceutical companies publish large datasets: an abundance of riches or fool's gold?

(2010) Sean Ekins et al.   DRUG DISCOVERY TODAY

A probabilistic approach to identify putative drug targets in biochemical networks

(2010) E. Murabito et al.   Journal of the Royal Society Interface

Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds

(2010) Gregory J. Crowther et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A Cell-Based High-Throughput Screen Validates the Plasmodial Surface Anion Channel As an Antimalarial Target

(2010) A. D. Pillai et al.   MOLECULAR PHARMACOLOGY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity

(2010) J. Marjanovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

(2010) Emily Peak et al.   PLoS Neglected Tropical Diseases

A Novel High Throughput Assay for Anthelmintic Drug Screening and Resistance Diagnosis by Real-Time Monitoring of Parasite Motility

(2010) Michael J. Smout et al.   PLoS Neglected Tropical Diseases

Cancer research: from folate antagonism to molecular targets

(2009) Joseph R. Bertino   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

(2009) Ivo Mueller et al.   LANCET INFECTIOUS DISEASES

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target

(2009) John G. Mina et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Automation of Science

(2009) Ross D. King et al.   SCIENCE

Small Molecule Subgraph Detector (SMSD) toolkit

(2009) Syed Rahman et al.   Journal of Cheminformatics

A New Purple Fluorescent Color Marker for Genetic Studies in Saccharomyces cerevisiae and Candida albicans

(2008) S. Keppler-Ross et al.   GENETICS