Efficacy, Safety, and Dose of Pafuramidine, a New Oral Drug for Treatment of First Stage Sleeping Sickness, in a Phase 2a Clinical Study and Phase 2b Randomized Clinical Studies

In VitroandIn VivoEvaluation of 28DAP010, a Novel Diamidine for Treatment of Second-Stage African Sleeping Sickness

(2014) Tanja Wenzler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies

(2014) Antoine Tarral et al.   CLINICAL PHARMACOKINETICS

Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis

(2012) P. P. SIMARRO et al.   PARASITOLOGY

Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

(2012) John K. Thuita et al.   PLoS Neglected Tropical Diseases

The Human African Trypanosomiasis Control and Surveillance Programme of the World Health Organization 2000–2009: The Way Forward

(2011) Pere P. Simarro et al.   PLoS Neglected Tropical Diseases

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

(2011) Robert T. Jacobs et al.   PLoS Neglected Tropical Diseases

Socio–economic aspects of neglected diseases: sleeping sickness and visceral leishmaniasis

(2010) M. Boelaert et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

(2009) T. Wenzler et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

(2009) Gerardo Priotto et al.   LANCET

Cardiac Alterations in Human African Trypanosomiasis (T.b. gambiense) with Respect to the Disease Stage and Antiparasitic Treatment

(2009) Johannes A. Blum et al.   PLoS Neglected Tropical Diseases

Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis

(2008) J.K. Thuita et al.   ACTA TROPICA

Efficacy of the Novel Diamidine Compound 2,5-Bis(4-Amidinophenyl)- Furan-Bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense Infection in Vervet Monkeys after Oral Administration

(2008) R. E. Mdachi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY