Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review
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Title
Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review
Authors
Keywords
Pregnancy, Pharmacokinetics, Drug distribution, Drug excretion, Antimalarials, Antiretrovirals, Drug metabolism, Obstetrics and gynecology
Journal
PLOS MEDICINE
Volume 13, Issue 11, Pages e1002160
Publisher
Public Library of Science (PLoS)
Online
2016-11-02
DOI
10.1371/journal.pmed.1002160
References
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- (2015) John M. Benjamin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2015) Minh P Lê et al. ANTIVIRAL THERAPY
- Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement
- (2015) Salmaan Kanji et al. CLINICAL PHARMACOKINETICS
- Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics
- (2015) A Olagunju et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Pharmacokinetics of tenofovir during pregnancy and postpartum
- (2015) BM Best et al. HIV MEDICINE
- Pharmacokinetics of nifedipine slow-release during sustained tocolysis
- (2015) Maureen A. ter Laak et al. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
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- (2015) Alice Stek et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
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- (2015) Karel Allegaert et al. BMC Anesthesiology
- Ondansetron Pharmacokinetics in Pregnant Women and Neonates: Towards a New Treatment for Neonatal Abstinence Syndrome
- (2015) MH Elkomy et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Randomized Clinical Trial Comparing the Pharmacokinetics of Standard- and Increased-Dosage Lopinavir-Ritonavir Coformulation Tablets in HIV-Positive Pregnant Women
- (2014) M. Santini-Oliveira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Population Pharmacokinetics and Clinical Response for Artemether-Lumefantrine in Pregnant and Nonpregnant Women with Uncomplicated Plasmodium falciparum Malaria in Tanzania
- (2014) Dominic Mosha et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Atazanavir exposure is effective during pregnancy, regardless of tenofovir use
- (2014) Angela Colbers et al. ANTIVIRAL THERAPY
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- (2014) D. Heather Watts et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
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- (2014) I. Valea et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
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- (2010) Kristel Van Calsteren et al. ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
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- (2010) S. Eyal et al. DRUG METABOLISM AND DISPOSITION
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- (2010) JS Lambert et al. HIV MEDICINE
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- (2008) Andreas Austgulen Westin et al. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
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