Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?

Title
Does High-Dose Antimicrobial Chemotherapy Prevent the Evolution of Resistance?
Authors
Keywords
Evolutionary emergence, Therapeutic window method, High-dose chemotherapy, Probability density, Antimicrobial resistance, Drug therapy, Microbial evolution, Evolutionary theory
Journal
PLoS Computational Biology
Volume 12, Issue 1, Pages e1004689
Publisher
Public Library of Science (PLoS)
Online
2016-01-29
DOI
10.1371/journal.pcbi.1004689

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