The path of least resistance: aggressive or moderate treatment?

Antibiotic Administration Routes Significantly Influence the Levels of Antibiotic Resistance in Gut Microbiota

(2013) Lu Zhang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A controlled, parallel, cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of Plasmodium falciparum in Burkina Faso

(2013) Alfred B Tiono et al.   MALARIA JOURNAL

Evolutionary rescue from extinction is contingent on a lower rate of environmental change

(2013) Haley A. Lindsey et al.   NATURE

Safety, Adherence and Acceptability of Intermittent Tenofovir/Emtricitabine as HIV Pre-Exposure Prophylaxis (PrEP) among HIV-Uninfected Ugandan Volunteers Living in HIV-Serodiscordant Relationships: A Randomized, Clinical Trial

(2013) Freddie M. Kibengo et al.   PLoS One

Aggressive Chemotherapy and the Selection of Drug Resistant Pathogens

(2013) Silvie Huijben et al.   PLoS Pathogens

Consequences of resistance:in vitrofitness,in vivoinfectivity, and transmissibility of oseltamivir-resistant influenza A viruses

(2012) Elena A. Govorkova   Influenza and Other Respiratory Viruses

Concentration-resistance relationships with Pseudomonas aeruginosa exposed to doripenem and ciprofloxacin in an in vitro model

(2012) S. H. Zinner et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

(2012) Aung Pyae Phyo et al.   LANCET

“One-Size-Fits-All”? Optimizing Treatment Duration for Bacterial Infections

(2012) Patricia Geli et al.   PLoS One

Intermittent Treatment to Prevent Pregnancy Malaria Does Not Confer Benefit in an Area of Widespread Drug Resistance

(2011) W. E. Harrington et al.   CLINICAL INFECTIOUS DISEASES

Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

(2011) Johan W. Mouton et al.   DRUG RESISTANCE UPDATES

Preserving the Lifesaving Power of Antimicrobial Agents

(2011) James M. Hughes   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The emergence of pan-resistant Gram-negative pathogens merits a rapid global political response

(2011) T. R. Walsh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multidrug-Resistant Tuberculosis Not Due to Noncompliance but to Between-Patient Pharmacokinetic Variability

(2011) Shashikant Srivastava et al.   JOURNAL OF INFECTIOUS DISEASES

The Threat of Artemisinin-Resistant Malaria

(2011) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

(2011) A. F. Read et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complexity of the adherence-response relationship in tuberculosis treatment: why are we still in the dark and how can we get out?

(2011) Jossy van den Boogaard et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

(2011) Erik Gullberg et al.   PLoS Pathogens

Intra- and Interhost Evolutionary Dynamics of Equine Influenza Virus

(2010) P. R. Murcia et al.   JOURNAL OF VIROLOGY

Gel versus capillary electrophoresis genotyping for categorizing treatment outcomes in two anti-malarial trials in Uganda

(2010) Vinay Gupta et al.   MALARIA JOURNAL

The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts

(2010) R. Craig MacLean et al.   NATURE REVIEWS GENETICS

Antibiotic resistance—What’s dosing got to do with it?

(2009) Jason A. Roberts et al.   CRITICAL CARE MEDICINE

Effect of Duration and Intermittency of Rifampin on Tuberculosis Treatment Outcomes: A Systematic Review and Meta-Analysis

(2009) Dick Menzies et al.   PLOS MEDICINE

Differential impact of adherence on long-term treatment response among naive HIV-infected individuals

(2008) Viviane D Lima et al.   AIDS

A unified anti-mutant dosing strategy

(2008) X. Zhao et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antiviral resistance and the control of pandemic influenza: The roles of stochasticity, evolution and model details

(2008) Andreas Handel et al.   JOURNAL OF THEORETICAL BIOLOGY

Decomposing health: tolerance and resistance to parasites in animals

(2008) L. Raberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Short-course antibiotic treatment in acute exacerbations of chronic bronchitis and COPD: a meta-analysis of double-blind studies

(2008) R El Moussaoui et al.   THORAX

Changes in Escherichia coli resistance patterns during and after antibiotic therapy: a longitudinal study among outpatients in Germany

(2007) E. Raum et al.   CLINICAL MICROBIOLOGY AND INFECTION