Aggressive Chemotherapy and the Selection of Drug Resistant Pathogens

When the Most Potent Combination of Antibiotics Selects for the Greatest Bacterial Load: The Smile-Frown Transition

(2014) Rafael Pena-Miller et al.   PLOS BIOLOGY

Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

(2012) Marilyn N. Martinez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evolutionary Approaches to Prolong Progression-Free Survival in Breast Cancer

(2012) A. S. Silva et al.   CANCER RESEARCH

Get pigs off antibiotics

(2012) Frank Aarestrup   NATURE

“One-Size-Fits-All”? Optimizing Treatment Duration for Bacterial Infections

(2012) Patricia Geli et al.   PLoS One

Enhanced Transmission of Drug-Resistant Parasites to Mosquitoes following Drug Treatment in Rodent Malaria

(2012) Andrew S. Bell et al.   PLoS One

Impact of antimicrobial stewardship in critical care: a systematic review

(2011) R. Kaki et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

5 versus 10 days of treatment with ceftriaxone for bacterial meningitis in children: a double-blind randomised equivalence study

(2011) Elizabeth Molyneux et al.   LANCET

Population biological principles of drug-resistance evolution in infectious diseases

(2011) Pia Abel zur Wiesch et al.   LANCET INFECTIOUS DISEASES

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

(2011) A. F. Read et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Procalcitonin measurements for guiding antibiotic treatment in pediatric pneumonia

(2011) Susanna Esposito et al.   RESPIRATORY MEDICINE

Differing Effects of Combination Chemotherapy with Meropenem and Tobramycin on Cell Kill and Suppression of Resistance of Wild-Type Pseudomonas aeruginosa PAO1 and Its Isogenic MexAB Efflux Pump-Overexpressed Mutant

(2009) G. L. Drusano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Short versus long duration of antibiotic therapy for bacterial meningitis: a meta-analysis of randomised controlled trials in children

(2009) D E Karageorgopoulos et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Adaptive Therapy

(2009) R. A. Gatenby et al.   CANCER RESEARCH

Antibiotic resistance—What’s dosing got to do with it?

(2009) Jason A. Roberts et al.   CRITICAL CARE MEDICINE

A change of strategy in the war on cancer

(2009) Robert A. Gatenby   NATURE

The epidemiological fitness cost of drug resistance in Mycobacterium tuberculosis

(2009) F. Luciani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding and Predicting Strain‐Specific Patterns of Pathogenesis in the Rodent Malaria Plasmodium chabaudi

(2008) Nicole Mideo et al.   AMERICAN NATURALIST

Impact of Short‐Course Quinolone Therapy on Susceptible and Resistant Populations ofStaphylococcus aureus

(2008) G. L. Drusano et al.   JOURNAL OF INFECTIOUS DISEASES

Exploring the role of the immune response in preventing antibiotic resistance

(2008) Andreas Handel et al.   JOURNAL OF THEORETICAL BIOLOGY

Does the drug sensitivity of malaria parasites depend on their virulence?

(2008) Petra Schneider et al.   MALARIA JOURNAL

Accelerated evolution of resistance in multidrug environments

(2008) M. Hegreness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE