Integrating Antimicrobial Therapy with Host Immunity to Fight Drug-Resistant Infections: Classical vs. Adaptive Treatment

A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

(2015) Elsje Pienaar et al.   JOURNAL OF THEORETICAL BIOLOGY

Targeting virulence: can we make evolution-proof drugs?

(2014) Richard C. Allen et al.   NATURE REVIEWS MICROBIOLOGY

The path of least resistance: aggressive or moderate treatment?

(2014) R. D. Kouyos et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

When the Most Potent Combination of Antibiotics Selects for the Greatest Bacterial Load: The Smile-Frown Transition

(2014) Rafael Pena-Miller et al.   PLOS BIOLOGY

Predicted Impact of Mass Drug Administration on the Development of Protective Immunity against Schistosoma haematobium

(2014) Kate M. Mitchell et al.   PLoS Neglected Tropical Diseases

Resource Competition May Lead to Effective Treatment of Antibiotic Resistant Infections

(2013) Antonio L. C. Gomes et al.   PLoS One

The complex pathogenesis of bacteremia

(2013) Eirini Christaki et al.   Virulence

Aggressive Chemotherapy and the Selection of Drug Resistant Pathogens

(2013) Silvie Huijben et al.   PLoS Pathogens

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

“One-Size-Fits-All”? Optimizing Treatment Duration for Bacterial Infections

(2012) Patricia Geli et al.   PLoS One

THE EVOLUTIONARY EPIDEMIOLOGY OF MULTILOCUS DRUG RESISTANCE

(2011) Troy Day et al.   EVOLUTION

The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy

(2011) A. F. Read et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccination by delayed treatment of infection

(2011) Sean P. Stromberg et al.   VACCINE

Age-related deregulation of naive T cell homeostasis in elderly humans

(2010) Sara Ferrando-Martínez et al.   AGE

Surveillance and Correlation of Antibiotic Prescription and Resistance of Gram-Negative Bacteria in Singaporean Hospitals

(2010) L.-Y. Hsu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hospital and Societal Costs of Antimicrobial‐Resistant Infections in a Chicago Teaching Hospital: Implications for Antibiotic Stewardship

(2009) Rebecca R. Roberts et al.   CLINICAL INFECTIOUS DISEASES

The changing epidemiology of resistance

(2009) P. M. Hawkey et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Recurrent Clostridium difficile infection: A review of risk factors, treatments, and outcomes

(2009) Stuart Johnson   JOURNAL OF INFECTION

Evolutionary Epidemiology of Drug-Resistance in Space

(2009) Florence Débarre et al.   PLoS Computational Biology

The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa

(2009) R. Craig MacLean et al.   PLoS Genetics

Life after the thymus: CD31+ and CD31- human naive CD4+ T-cell subsets

(2008) S. Kohler et al.   BLOOD

Exploring the role of the immune response in preventing antibiotic resistance

(2008) Andreas Handel et al.   JOURNAL OF THEORETICAL BIOLOGY

Modelling within-Host Spatiotemporal Dynamics of Invasive Bacterial Disease

(2008) Andrew J Grant et al.   PLOS BIOLOGY