A Network Model to Describe the Terminal Differentiation of B Cells

The regulatory network that controls the differentiation of T lymphocytes

(2013) Pablo Martínez-Sosa et al.   BIOSYSTEMS

IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts

(2013) L. J. Berglund et al.   BLOOD

Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4

(2013) Kyoko Ochiai et al.   IMMUNITY

Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms

(2013) Chuanxin Huang et al.   NATURE IMMUNOLOGY

All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2013) Qiang Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pathogenesis of Human B Cell Lymphomas

(2012) Arthur L. Shaffer et al.   Annual Review of Immunology

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

The Cell Collective: Toward an open and collaborative approach to systems biology

(2012) Tomáš Helikar et al.   BMC Systems Biology

B Cell Receptor-ERK1/2 Signal Cancels PAX5-Dependent Repression of BLIMP1 through PAX5 Phosphorylation: A Mechanism of Antigen-Triggering Plasma Cell Differentiation

(2012) T. Yasuda et al.   JOURNAL OF IMMUNOLOGY

Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesis

(2012) M. R. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiparametric Flow Cytometry for Identification and Fluorescence Activated Cell Sorting of Five Distinct B-Cell Subpopulations in Normal Tonsil Tissue

(2011) Malene Krag Kjeldsen et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post-Darwinian biology?

(2011) Sui Huang   BIOESSAYS

Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation

(2011) Jukka Alinikula et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues

(2011) Jared B. Hawkins et al.   PLoS One

ERKs Induce Expression of the Transcriptional Repressor Blimp-1 and Subsequent Plasma Cell Differentiation

(2011) T. Yasuda et al.   Science Signaling

The genetic network controlling plasma cell differentiation

(2011) Stephen L. Nutt et al.   SEMINARS IN IMMUNOLOGY

In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo

(2011) Takuya Nojima et al.   Nature Communications

BoolNet—an R package for generation, reconstruction and analysis of Boolean networks

(2010) Christoph Müssel et al.   BIOINFORMATICS

Human peripheral blood B-cell compartments: A crossroad in B-cell traffic

(2010) M. Perez-Andres et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch

(2010) Akihiko Muto et al.   EMBO JOURNAL

The germinal center reaction

(2010) Dominique Gatto et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

(2010) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell–intrinsic mechanism

(2010) Dimitra Zotos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pillars Article: Blimp-1, a Novel Zinc Finger-Containing Protein That Can Drive the Maturation of B Lymphocytes into Immunoglobulin-Secreting Cells. Cell. 1994. 77: 297-306

(2010) C. A. Turner et al.   JOURNAL OF IMMUNOLOGY

IL-21 Receptor Is Critical for the Development of Memory B Cell Responses

(2010) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

The Arabidopsis thaliana flower organ specification gene regulatory network determines a robust differentiation process

(2010) Yara-Elena Sánchez-Corrales et al.   JOURNAL OF THEORETICAL BIOLOGY

Attraction Basins as Gauges of Robustness against Boundary Conditions in Biological Complex Systems

(2010) Jacques Demongeot et al.   PLoS One

BCL6 promoter interacts with far upstream sequences with greatly enhanced activating histone modifications in germinal center B cells

(2010) H. Ramachandrareddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Bistable Switch Underlying B-Cell Differentiation and Its Disruption by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-dioxin

(2010) Sudin Bhattacharya et al.   TOXICOLOGICAL SCIENCES

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells

(2009) K. Basso et al.   BLOOD

Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright

(2009) Christian Schmidt et al.   EMBO JOURNAL

Stepwise Activation of Enhancer and Promoter Regions of the B Cell Commitment Gene Pax5 in Early Lymphopoiesis

(2009) Thorsten Decker et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

(2009) Derrick J. Todd et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

(2009) Thinh Huy Tran et al.   NATURE IMMUNOLOGY

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE