Population Density Modulates Drug Inhibition and Gives Rise to Potential Bistability of Treatment Outcomes for Bacterial Infections

Prediction of multidimensional drug dose responses based on measurements of drug pairs

(2016) Anat Zimmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrating Antimicrobial Therapy with Host Immunity to Fight Drug-Resistant Infections: Classical vs. Adaptive Treatment

(2016) Erida Gjini et al.   PLoS Computational Biology

Isolated cell behavior drives the evolution of antibiotic resistance

(2015) T. Artemova et al.   Molecular Systems Biology

Bacterial Temporal Dynamics Enable Optimal Design of Antibiotic Treatment

(2015) Hannah R. Meredith et al.   PLoS Computational Biology

The enduring utility of continuous culturing in experimental evolution

(2014) David Gresham et al.   GENOMICS

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

(2014) Kıvanç Birsoy et al.   NATURE

The Influence of Urinary pH on Antibiotic Efficacy Against Bacterial Uropathogens

(2014) Luo Yang et al.   UROLOGY

A Low Cost, Customizable Turbidostat for Use in Synthetic Circuit Characterization

(2014) Chris N. Takahashi et al.   ACS Synthetic Biology

Uncovering Scaling Laws to Infer Multidrug Response of Resistant Microbes and Cancer Cells

(2014) Kevin B. Wood et al.   Cell Reports

Bacterial cheating drives the population dynamics of cooperative antibiotic resistance plasmids

(2013) Eugene A Yurtsev et al.   Molecular Systems Biology

Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition

(2013) Erdal Toprak et al.   Nature Protocols

In Vitro Activity of Daptomycin against Enterococcus faecalis under Various Conditions of Growth-Phases, Inoculum and pH

(2013) Xavier Argemi et al.   PLoS One

Drosophila Host Model Reveals New Enterococcus faecalis Quorum-Sensing Associated Virulence Factors

(2013) Neuza Teixeira et al.   PLoS One

The Innate Growth Bistability and Fitness Landscapes of Antibiotic-Resistant Bacteria

(2013) J. B. Deris et al.   SCIENCE

Mechanism-independent method for predicting response to multidrug combinations in bacteria

(2012) Kevin Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative Genomics of Enterococci: Variation in Enterococcus faecalis, Clade Structure in E. faecium, and Defining Characteristics of E. gallinarum and E. casseliflavus

(2012) K. L. Palmer et al.   mBio

Intrinsic and acquired resistance mechanisms in enterococcus

(2012) Brian L. Hollenbeck et al.   Virulence

The incongruent gelatinase genotype and phenotype in Enterococcus faecalis are due to shutting off the ability to respond to the gelatinase biosynthesis-activating pheromone (GBAP) quorum-sensing signal

(2011) N. Teixeira et al.   MICROBIOLOGY-SGM

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Bacterial charity work leads to population-wide resistance

(2010) Henry H. Lee et al.   NATURE

A synchronized quorum of genetic clocks

(2010) Tal Danino et al.   NATURE

Mechanism of chromosomal transfer of Enterococcus faecalis pathogenicity island, capsule, antimicrobial resistance, and other traits

(2010) J. M. Manson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimal Drug Synergy in Antimicrobial Treatments

(2010) Joseph Peter Torella et al.   PLoS Computational Biology

Functional relationship between bacterial cell density and the efficacy of antibiotics

(2009) K. I. Udekwu et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A fratricidal mechanism is responsible for eDNA release and contributes to biofilm development ofEnterococcus faecalis

(2009) Vinai Chittezham Thomas et al.   MOLECULAR MICROBIOLOGY

Regulation of Autolysis-Dependent Extracellular DNA Release by Enterococcus faecalis Extracellular Proteases Influences Biofilm Development

(2008) V. C. Thomas et al.   JOURNAL OF BACTERIOLOGY

Stochastic switching as a survival strategy in fluctuating environments

(2008) Murat Acar et al.   NATURE GENETICS

Accelerated evolution of resistance in multidrug environments

(2008) M. Hegreness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug interactions modulate the potential for evolution of resistance

(2008) J.-B. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA