Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology
Authors
Keywords
-
Journal
Journal of Analytical Methods in Chemistry
Volume 2016, Issue -, Pages 1-16
Publisher
Hindawi Limited
Online
2016-12-29
DOI
10.1155/2016/4156293
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Preventive effect of a novel diosgenin derivative on arterial and venous thrombosis in vivo
- (2016) Huajie Zheng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diosgenin effectively suppresses skin inflammation induced by phthalic anhydride in IL-4/Luc/CNS-1 transgenic mice
- (2016) Ji Eun Kim et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Quantitative determination of sarsasapogenin in rat plasma using liquid chromatography-tandem mass spectrometry
- (2016) Bo Yang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- A more ecological and efficient approach for producing diosgenin from Dioscorea zingiberensis tubers via pressurized biphase acid hydrolysis
- (2016) Huan Yang et al. JOURNAL OF CLEANER PRODUCTION
- Purification and characterization of a glycosidase with hydrolyzing multi-3-O-glycosides of spirostanol saponin activity from Gibberella intermedia
- (2016) Hui Li et al. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
- Diosgenin regulates adipokine expression in perivascular adipose tissue and ameliorates endothelial dysfunction via regulation of AMPK
- (2016) Yan Chen et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Effects of total saponins from Rhizoma Dioscoreae Nipponicae on expression of vascular endothelial growth factor and angiopoietin-2 and Tie-2 receptors in the synovium of rats with rheumatoid arthritis
- (2016) Yachun Guo et al. Journal of the Chinese Medical Association
- Steroidal saponin diosgenin from Dioscorea bulbifera protects cardiac cells from hypoxia -reoxygenation injury through modulation of pro -survival and pro -death molecules
- (2016) AHannah Rachel Vasanthi et al. Pharmacognosy Magazine
- Renoprotective effect of diosgenin in streptozotocin induced diabetic rats
- (2016) Divya M. Kanchan et al. Pharmacological Reports
- Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells
- (2016) Shanshan Jiang et al. PHYTOMEDICINE
- Supramolecular prodrug micelles based on the complementary multiple hydrogen bonds as drug delivery platform for thrombosis therapy
- (2016) Wen'en Li et al. RSC Advances
- The Effect of Crude Diosgenin Extract from Purple and Yellow Greater Yams (Dioscorea alata L.) on the Lipid Profile of Dyslipidemia Rats
- (2016) Harijono Harijono et al. Emirates Journal of Food and Agriculture
- Diosgenin inhibits atherosclerosis via suppressing the MiR-19b-induced downregulation of ATP-binding cassette transporter A1
- (2015) Yun-cheng Lv et al. ATHEROSCLEROSIS
- Anticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm
- (2015) Samy Selim et al. BMC Complementary and Alternative Medicine
- Improving Bone Microarchitecture in Aging with Diosgenin Treatment: A Study in Senescence-Accelerated OXYS Rats
- (2015) Maria A. Tikhonova CHINESE JOURNAL OF PHYSIOLOGY
- Diosgenin prevents bone loss on retinoic acid-induced osteoporosis in rats
- (2015) S. Zhao et al. IRISH JOURNAL OF MEDICAL SCIENCE
- Diosgenin Mitigates Streptozotocin Diabetes-induced Vascular Dysfunction of the Rat Aorta
- (2015) Farshad Roghani-Dehkordi et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins: A comparative study
- (2015) Yi-Na Tang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Diosgenin Functionalized Iron Oxide Nanoparticles as Novel Nanomaterial Against Breast Cancer
- (2015) Sougata Ghosh et al. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
- An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice
- (2015) Keiko TAKETANI et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Antimicrobial and inhibition on heat-induced protein denaturation of constituents isolated fromPolygonatumverticillatumrhizomes
- (2015) Haroon Khan et al. NATURAL PRODUCT RESEARCH
- Microwave-assisted extraction and a new determination method for total steroid saponins from Dioscorea zingiberensis C.H. Wright
- (2015) Yao Ren et al. STEROIDS
- LC–MSn characterization of steroidal saponins in Helleborus niger L. roots and their conversion products during fermentation
- (2015) Sarina M. Duckstein et al. STEROIDS
- A self-assembled nanoparticle platform based on poly(ethylene glycol)–diosgenin conjugates for co-delivery of anticancer drugs
- (2015) Chunxiao Li et al. RSC Advances
- Diosgenin, 4-Hydroxyisoleucine, and Fiber from Fenugreek: Mechanisms of Actions and Potential Effects on Metabolic Syndrome
- (2015) Scott Fuller et al. Advances in Nutrition
- Sequential release of drugs from hollow manganese ferrite nanocarriers for breast cancer therapy
- (2015) B. N. Prashanth Kumar et al. Journal of Materials Chemistry B
- Diosgenin-induced protection against myocardial ischaemia-reperfusion injury is mediated by mitochondrial KATP channels in a rat model
- (2015) R Badalzadeh et al. PERFUSION-UK
- Diosgenin Inhibits hTERT Gene Expression in the A549 Lung Cancer Cell Line
- (2014) Rahmati Yamchi Mohammad et al. Asian Pacific Journal of Cancer Prevention
- Effect of β-Cyclodextrin Derivatives on the Diosgenin Absorption in Caco-2 Cell Monolayer and Rats
- (2014) Masaki Okawara et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Comparative analysis of diosgenin in Dioscorea species and related medicinal plants by UPLC-DAD-MS
- (2014) Tao Yi et al. BMC BIOCHEMISTRY
- Modulatory Effects of Diosgenin on Attenuating the Key Enzymes Activities of Carbohydrate Metabolism and Glycogen Content in Streptozotocin-Induced Diabetic Rats
- (2014) Ganapathy Saravanan et al. Canadian Journal of Diabetes
- Fenugreek seed extract and its phytocompounds- trigonelline and diosgenin arbitrate their hepatoprotective effects through attenuation of endoplasmic reticulum stress and oxidative stress in type 2 diabetic rats
- (2014) Tharaheswari Mayakrishnan et al. EUROPEAN FOOD RESEARCH AND TECHNOLOGY
- Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats
- (2014) Lamiaa A. Ahmed et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The effects of diosgenin in the Regulation of renal proximal tubular fibrosis
- (2014) Wei-Cheng Wang et al. EXPERIMENTAL CELL RESEARCH
- Extraction and quantification of saponins: A review
- (2014) Choon Yoong Cheok et al. FOOD RESEARCH INTERNATIONAL
- Diosgenin inhibits superoxide generation in FMLP-activated mouse neutrophils via multiple pathways
- (2014) Y. Lin et al. FREE RADICAL RESEARCH
- Direct Biotransformation of Dioscin into Diosgenin in Rhizome of Dioscorea zingiberensis by Penicillium dioscin
- (2014) Jingzhou Dong et al. INDIAN JOURNAL OF MICROBIOLOGY
- High-Dose Diosgenin Reduces Bone Loss in Ovariectomized Rats via Attenuation of the RANKL/OPG Ratio
- (2014) Zhiguo Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effect of liquid crystals with cyclodextrin on the bioavailability of a poorly water-soluble compound, diosgenin, after its oral administration to rats
- (2014) Masaki Okawara et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Anti-arrhythmic effect of diosgenin in reperfusion-induced myocardial injury in a rat model: activation of nitric oxide system and mitochondrial KATP channel
- (2014) Reza Badalzadeh et al. Journal of Physiological Sciences
- Diosgenin attenuates inflammatory response induced by myocardial reperfusion injury: role of mitochondrial ATP-sensitive potassium channels
- (2014) Hadi Ebrahimi et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line
- (2014) Mohammad Rahmati-Yamchi et al. MOLECULAR BIOLOGY REPORTS
- Diosgenin induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells
- (2014) YONGJIAN LI et al. ONCOLOGY REPORTS
- Diosgenin inhibits the migration of human breast cancer MDA-MB-231 cells by suppressing Vav2 activity
- (2014) Zhongmei He et al. PHYTOMEDICINE
- Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats
- (2014) Pazhanichamy Kalailingam et al. PHYTOMEDICINE
- Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase
- (2014) Sougata Ghosh et al. PLoS One
- Development of a new certified reference material of diosgenin using mass balance approach and Coulometric titration method
- (2014) Ningbo Gong et al. STEROIDS
- Synthesis of novel anticancer agents through opening of spiroacetal ring of diosgenin
- (2014) A.A. Hamid et al. STEROIDS
- Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease
- (2013) Hu Cai et al. ACTA PHARMACOLOGICA SINICA
- Chemical fingerprint analysis and quantitative determination of steroidal compounds fromDioscorea villosa,Dioscoreaspecies and dietary supplements using UHPLC-ELSD
- (2013) Bharathi Avula et al. BIOMEDICAL CHROMATOGRAPHY
- PPAR’s and Diosgenin a chemico biological insight in NIDDM
- (2013) M.K. Sangeetha et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Diosgenin quantification, characterisation and chemical composition in a tuber collection ofDioscoreaspp. in the state of Jalisco, Mexico
- (2013) María de Lourdes Contreras-Pacheco et al. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
- Rapid quantitative analysis of diosgenin in the tubers ofDioscorea zingiberensisC.H. Wright by coupling cellulose enzymolysis and two-phase acid hydrolysis in tandem with HPLC-UV
- (2013) Huan Yang et al. NATURAL PRODUCT RESEARCH
- Characterization of in Vitro ADME Properties of Diosgenin and Dioscin from Dioscorea villosa
- (2013) Vamshi Manda et al. PLANTA MEDICA
- Anti-thrombosis effect of diosgenyl saponins in vitro and in vivo
- (2013) Rui Zhang et al. STEROIDS
- Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D3-MARRS
- (2013) Chihiro Tohda et al. Scientific Reports
- Isolation and characterization of diosgenin from in vitro cultured tissues of Helicteres isora L
- (2013) Harshal A. Deshpande et al. PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS
- Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKβ and IRS-1 pathways
- (2012) Kang Liu et al. ATHEROSCLEROSIS
- Synthesis, characterization and biological studies of diosgenyl analogues
- (2012) Baozhan Huang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Diosgenin Induces Apoptosis in HepG2 Cells through Generation of Reactive Oxygen Species and Mitochondrial Pathway
- (2012) Dae Sung Kim et al. Evidence-based Complementary and Alternative Medicine
- Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs
- (2012) Zhu-Jun Mao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anticancer steroids: linking natural and semi-synthetic compounds
- (2012) Jorge A. R. Salvador et al. NATURAL PRODUCT REPORTS
- Antineoplastic and Apoptotic Potential of Traditional Medicines Thymoquinone and Diosgenin in Squamous Cell Carcinoma
- (2012) Subhasis Das et al. PLoS One
- Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells
- (2012) Qing-Yi Tong et al. STEROIDS
- Diosgenin, a Plant-Derived Sapogenin, Exhibits Antiviral Activityin Vitroagainst Hepatitis C Virus
- (2011) Ya-Jean Wang et al. JOURNAL OF NATURAL PRODUCTS
- Cancer Cell Signaling Pathways Targeted by Spice-Derived Nutraceuticals
- (2011) Bokyung Sung et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression
- (2011) Pin-Shern Chen et al. PLoS One
- A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma
- (2010) Jing Wang et al. ACTA PHARMACOLOGICA SINICA
- Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
- (2010) Feng Li et al. CANCER LETTERS
- Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells
- (2010) C. Lepage et al. CANCER LETTERS
- Diosgenin inhibits macrophage-derived inflammatory mediators through downregulation of CK2, JNK, NF-κB and AP-1 activation
- (2010) Da-Hye Jung et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice
- (2010) Taku Uemura et al. JOURNAL OF NUTRITION
- Diosgenin Modulates Vascular Smooth Muscle Cell Function by Regulating Cell Viability, Migration, and Calcium Homeostasis
- (2010) M. Esfandiarei et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues
- (2010) Taku Uemura et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Simultaneous analysis of diosgenin and sarsasapogenin in Asparagus officinalis byproduct by thin-layer chromatography
- (2010) Liwei Wang et al. PHYTOCHEMICAL ANALYSIS
- Saponins as cytotoxic agents: a review
- (2010) Irma Podolak et al. PHYTOCHEMISTRY REVIEWS
- Anti-thrombosis effect of diosgenin extract from Dioscorea zingiberensis C.H. Wright in vitro and in vivo
- (2010) Guohua Gong et al. PHYTOMEDICINE
- Determination of Diosgenin Content in Medicinal Plants with Enzyme-Linked Immunosorbent Assay
- (2010) Jiaru Li et al. PLANTA MEDICA
- Inhibition of TNF-α-induced adhesion molecule expression by diosgenin in mouse vascular smooth muscle cells via downregulation of the MAPK, Akt and NF-κB signaling pathways
- (2010) Ko-Woon Choi et al. VASCULAR PHARMACOLOGY
- Qualitative and Quantitative Analysis of Microbial Transformation of Steroidal Saponins in Dioscorea zingiberensis
- (2009) Shan-Shan Qi et al. CHROMATOGRAPHIA
- Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells
- (2009) Sowmyalakshmi Srinivasan et al. INTERNATIONAL JOURNAL OF CANCER
- Development and validation of a sensitive and rapid non-aqueous LC–ESI-MS/MS method for measurement of diosgenin in the plasma of normal and hyperlipidemic rats: A comparative study
- (2009) Lina Xu et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Cancer Chemopreventive and Therapeutic Effects of Diosgenin, a Food Saponin
- (2009) Jayadev Raju et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Diosgenin Attenuates Allergen-Induced Intestinal Inflammation and IgE Production in a Murine Model of Food Allergy
- (2009) Chung-Hsiung Huang et al. PLANTA MEDICA
- Efficient protocol for purification of diosgenin and two fatty acids fromRhizoma dioscoreaeby SFE coupled with high-speed counter-current chromatography and evaporative light scattering detection
- (2008) Youwei Xu et al. JOURNAL OF SEPARATION SCIENCE
- Metabolite profiling of saponins in Balanites aegyptiaca plant tissues using LC (RI)-ESI/MS and MALDI-TOF/MS
- (2008) Bishnu P. Chapagain et al. Metabolomics
- Development and validation of a liquid chromatography/tandem mass spectrometry assay for the quantification of methyl protodioscin in rat plasma: application to a pharmacokinetic study
- (2007) Xiuzhen Cao et al. BIOMEDICAL CHROMATOGRAPHY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More