Supramolecular prodrug micelles based on the complementary multiple hydrogen bonds as drug delivery platform for thrombosis therapy

Design, synthesis and evaluation of isoxazolo[5,4-d]pyrimidin-4(5H)-one derivatives as antithrombotic agents

(2015) Jiabin Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase

(2015) Mingyi Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of novel anticancer agents through opening of spiroacetal ring of diosgenin

(2014) A.A. Hamid et al.   STEROIDS

Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores

(2013) Uroš Trstenjak et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anti-thrombosis effect of diosgenyl saponins in vitro and in vivo

(2013) Rui Zhang et al.   STEROIDS

Cytotoxicity and apoptosis-inducing effect of steroidal saponins from Dioscorea zingiberensis Wright against cancer cells

(2012) Qing-Yi Tong et al.   STEROIDS

Venous Thromboembolism

(2010) Michele G. Beckman et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

pH-Sensitive Micelles Self-Assembled from Amphiphilic Copolymer Brush for Delivery of Poorly Water-Soluble Drugs

(2010) You Qiang Yang et al.   BIOMACROMOLECULES

Protective effects of diosgenin in the hyperlipidemic rat model and in human vascular endothelial cells against hydrogen peroxide-induced apoptosis

(2010) Guohua Gong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-thrombotic activity and chemical characterization of steroidal saponins from Dioscorea zingiberensis C.H. Wright

(2010) Hua Li et al.   FITOTERAPIA

Self-Assembled Micelles from an Amphiphilic Hyperbranched Copolymer with Polyphosphate Arms for Drug Delivery

(2010) Jinyao Liu et al.   LANGMUIR

Anti-thrombosis effect of diosgenin extract from Dioscorea zingiberensis C.H. Wright in vitro and in vivo

(2010) Guohua Gong et al.   PHYTOMEDICINE

Self-Assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery

(2009) Jinyao Liu et al.   BIOMATERIALS

Randomized Trial of Warfarin, Aspirin, and Clopidogrel in Patients With Chronic Heart Failure

(2009) Barry M. Massie et al.   CIRCULATION

Acute toxicity and sub-chronic toxicity of steroidal saponins from Dioscorea zingiberensis C.H.Wright in rodents

(2009) Yuan Qin et al.   JOURNAL OF ETHNOPHARMACOLOGY

The anticoagulants market

(2009) Irena Melnikova   NATURE REVIEWS DRUG DISCOVERY

Synthesis and self-assembly of amphiphilic poly(acrylic acid-b-dl-lactide) to form micelles for pH-responsive drug delivery

(2009) Ya-Nan Xue et al.   POLYMER

pH-Controllable Supramolecular Systems

(2008) Ken Cham-Fai Leung et al.   Chemistry-An Asian Journal

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

Self-Assembled Micelles of Biodegradable Triblock Copolymers Based on Poly(ethyl ethylene phosphate) and Poly(ϵ-caprolactone) as Drug Carriers

(2007) Yu-Cai Wang et al.   BIOMACROMOLECULES