Hedgehog pathway is involved in nitidine chloride induced inhibition of epithelial-mesenchymal transition and cancer stem cells-like properties in breast cancer cells

Oct-4 and nanog promote the epithelial-mesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients

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Impact of breast cancer treatments on sleep disturbances – A systematic review

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Nitidine chloride induces apoptosis, cell cycle arrest, and synergistic cytotoxicity with doxorubicin in breast cancer cells

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Huaier aqueous extract inhibits stem-like characteristics of MCF7 breast cancer cells via inactivation of hedgehog pathway

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Nitidine chloride inhibits renal cancer cell metastasis via suppressing AKT signaling pathway

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SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway

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Cancer Stem Cells and Novel Targets for Antitumor Strategies

(2012) Gerald J. Prud’homme   CURRENT PHARMACEUTICAL DESIGN

Notch signaling mediates TGF-β1-induced epithelial–mesenchymal transition through the induction of Snai1

(2012) Yosuke Matsuno et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kappaB pathway in RAW 264.7 cells

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Biological activities of nitidine, a potential anti-malarial lead compound

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Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures

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Nitidine Chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway

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Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression

(2011) Marcus E. Peter   CELL CYCLE

Inhibition of STAT3 Signaling Pathway by Nitidine Chloride Suppressed the Angiogenesis and Growth of Human Gastric Cancer

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Epithelial–mesenchymal transition in the skin

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Arsenic-Specific Stem Cell Selection During Malignant Transformation

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Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways

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Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer

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Epithelial-Mesenchymal Transitions in Development and Disease

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The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies

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Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

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Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

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Epithelial-Mesenchymal Transition and the Stem Cell Phenotype

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A paracrine requirement for hedgehog signalling in cancer

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Transcriptional regulation of cell polarity in EMT and cancer

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