Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures

Off-Target Function of the Sonic Hedgehog Inhibitor Cyclopamine in Mediating Apoptosis via Nitric Oxide-Dependent Neutral Sphingomyelinase 2/Ceramide Induction

(2012) M. Meyers-Needham et al.   MOLECULAR CANCER THERAPEUTICS

Human Glioblastoma Stem-Like Cells are More Sensitive to Allogeneic NK and T Cell-Mediated Killing Compared with Serum-Cultured Glioblastoma Cells

(2011) Tony Avril et al.   BRAIN PATHOLOGY

Autophagy inhibition cooperates with erlotinib to induce glioblastoma cell death

(2011) Sandrine Eimer et al.   CANCER BIOLOGY & THERAPY

Eyes Wide Open: A Critical Review of Sphere-Formation as an Assay for Stem Cells

(2011) Erika Pastrana et al.   Cell Stem Cell

Role of sonic hedgehog signaling in migration of cell lines established from CD133-positive malignant glioma cells

(2011) Hiroyuki Uchida et al.   JOURNAL OF NEURO-ONCOLOGY

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas

(2010) Hongwu Zheng et al.   CANCER CELL

Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells

(2010) T. Mazumdar et al.   CANCER RESEARCH

Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies

(2010) Tetyana Denysenko et al.   CELL BIOCHEMISTRY AND FUNCTION

Cancer Stem Cells and Self-renewal

(2010) C. A. O'Brien et al.   CLINICAL CANCER RESEARCH

Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies

(2010) Monika Witusik-Perkowska et al.   JOURNAL OF NEURO-ONCOLOGY

Sonic Hedgehog signaling in the mammalian brain

(2010) Elisabeth Traiffort et al.   JOURNAL OF NEUROCHEMISTRY

Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions

(2010) Tony Avril et al.   JOURNAL OF NEUROIMMUNOLOGY

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

(2010) Adan Aguirre et al.   NATURE

Innovative Therapies for Children with Cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors

(2010) B. Geoerger et al.   NEURO-ONCOLOGY

Antitumor Effects of a Combined 5-Aza-2'Deoxycytidine and Valproic Acid Treatment on Rhabdomyosarcoma and Medulloblastoma in Ptch Mutant Mice

(2009) I. Ecke et al.   CANCER RESEARCH

Multipotent CD15+ Cancer Stem Cells in Patched-1-Deficient Mouse Medulloblastoma

(2009) R. J. Ward et al.   CANCER RESEARCH

Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer

(2009) Maria–Theresa Mueller et al.   GASTROENTEROLOGY

Turning Cancer Stem Cells Inside Out: An Exploration of Glioma Stem Cell Signaling Pathways

(2009) Zhizhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma

(2009) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)

(2008) Xiaomei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer Stem Cells: A Step Toward the Cure

(2008) Bruce M. Boman et al.   JOURNAL OF CLINICAL ONCOLOGY

Don't Look: Growing Clonal Versus Nonclonal Neural Stem Cell Colonies

(2008) Brenda L.K. Coles-Takabe et al.   STEM CELLS