Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis

Genetics of systemic lupus erythematosus: immune responses and end organ resistance to damage

(2014) Chao Dai et al.   CURRENT OPINION IN IMMUNOLOGY

Genetic Variants in Genes of the Inflammatory Response in Association with Infective Endocarditis

(2014) Melanie Weinstock et al.   PLoS One

Gene-Centric Analysis Identifies Variants Associated With Interleukin-6 Levels and Shared Pathways With Other Inflammation Markers

(2013) Tina Shah et al.   Circulation-Cardiovascular Genetics

IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential

(2012) Shu Zhu et al.   CLINICAL SCIENCE

Inflammatory Mechanisms in Atherosclerosis: The Impact of Matrix Metalloproteinases

(2012) Gerasimos Siasos et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus

(2011) E. Sanchez et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon regulatory factor 5 is critical for the development of lupus in MRL/lpr mice

(2011) Yoshifumi Tada et al.   ARTHRITIS AND RHEUMATISM

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

(2011) D. A. Hume et al.   BLOOD

Pathophysiology of rheumatoid arthritis

(2011) Faye AH Cooles et al.   CURRENT OPINION IN RHEUMATOLOGY

Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?

(2011) Garth L. Burn et al.   FEBS LETTERS

New IBD genetics: common pathways with other diseases

(2011) C. W. Lees et al.   GUT

Crohnʼs disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy

(2011) Michael Scharl et al.   INFLAMMATORY BOWEL DISEASES

Distinct Regulation of Murine Lupus Susceptibility Genes by the IRF5/Blimp-1 Axis

(2011) R. Panchanathan et al.   JOURNAL OF IMMUNOLOGY

PPARγ expression is increased in systemic lupus erythematosus patients and represses CD40/CD40L signaling pathway

(2011) DS Oxer et al.   LUPUS

Genomics and the Multifactorial Nature of Human Autoimmune Disease

(2011) Judy H. Cho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

(2011) Paula S. Ramos et al.   PLoS Genetics

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

(2011) Deborah S. Cunninghame Graham et al.   PLoS Genetics

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

(2010) G. Orozco et al.   ANNALS OF THE RHEUMATIC DISEASES

Toxicological Disruption of Signaling Homeostasis: Tyrosine Phosphatases as Targets

(2010) James M. Samet et al.   Annual Review of Pharmacology and Toxicology

Association of a functional IRF7 variant with systemic lupus erythematosus

(2010) Qiong Fu et al.   ARTHRITIS AND RHEUMATISM

Regulation of immunity and oncogenesis by the IRF transcription factor family

(2010) David Savitsky et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles

(2010) M L Budarf et al.   GENES AND IMMUNITY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse

(2010) Syed-Wajahat Hassan et al.   PLoS One

Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases

(2010) Stephanie M. Stanford et al.   Seminars in Immunopathology

Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis

(2010) Young Hee Rho et al.   ARTHRITIS CARE & RESEARCH

Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis

(2009) Young Hee Rho et al.   ARTHRITIS AND RHEUMATISM

The Relation of Genetic and Environmental Factors to Systemic Inflammatory Biomarker Concentrations

(2009) Renate B. Schnabel et al.   Circulation-Cardiovascular Genetics

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

Autoimmunity risk alleles in costimulation pathways

(2009) Lisa M. Maier et al.   IMMUNOLOGICAL REVIEWS

T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease

(2009) Karen M. Doody et al.   IMMUNOLOGICAL REVIEWS

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease

(2008) Grace Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Inflammation‐associated insulin resistance: Differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms

(2008) Cecilia P. Chung et al.   ARTHRITIS AND RHEUMATISM

Detecting shared pathogenesis from the shared genetics of immune-related diseases

(2008) Alexandra Zhernakova et al.   NATURE REVIEWS GENETICS

Advances in the genetics of rheumatoid arthritis point to subclassification into distinct disease subsets

(2008) Annette HM van der Helm-van Mil et al.   ARTHRITIS RESEARCH & THERAPY