Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo

Switchable Water-Adhesive, Superhydrophobic Palladium-Layered Silicon Nanowires Potentiate the Angiogenic Efficacy of Human Stem Cell Spheroids

(2014) Jungmok Seo et al.   ADVANCED MATERIALS

Combinatorially Designed Lipid-like Nanoparticles for Intracellular Delivery of Cytotoxic Protein for Cancer Therapy

(2014) Ming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

(2014) H. Razavi et al.   JOURNAL OF VIRAL HEPATITIS

Phosphorylation of Hepatitis C Virus RNA Polymerases Ser29 and Ser42 by Protein Kinase C-Related Kinase 2 Regulates Viral RNA Replication

(2014) S.-H. Han et al.   JOURNAL OF VIROLOGY

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

(2014) Kathryn A. Whitehead et al.   Nature Communications

Enhanced Intracellular siRNA Delivery using Bioreducible Lipid-Like Nanoparticles

(2014) Ming Wang et al.   Advanced Healthcare Materials

The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

(2013) Hiroto Hatakeyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Gene delivery platforms

(2013) Jong-Myung Kim et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

DOPE facilitates quaternized lipidoids (QLDs) for in vitro DNA delivery

(2013) Shuo Sun et al.   Nanomedicine-Nanotechnology Biology and Medicine

Effect of polyethyleneglycol (PEG) chain length on the bio–nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells

(2013) Daniela Pozzi et al.   Nanoscale

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

Targeting receptor-mediated endocytotic pathways with nanoparticles: Rationale and advances

(2012) Shi Xu et al.   ADVANCED DRUG DELIVERY REVIEWS

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation

(2012) Mi-Gyeong Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sonic hedgehog intradermal gene therapy using a biodegradable poly(β-amino esters) nanoparticle to enhance wound healing

(2012) Hyun-Ji Park et al.   BIOMATERIALS

A Combinatorial Library of Unsaturated Lipidoids for Efficient Intracellular Gene Delivery

(2012) Ming Wang et al.   ACS Synthetic Biology

Hepatocyte-Targeting Single Galactose-Appended Naphthalimide: A Tool for Intracellular Thiol Imaging in Vivo

(2011) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

Targeted Delivery of siRNA to Hepatocytes and Hepatic Stellate Cells by Bioconjugation

(2010) Lin Zhu et al.   BIOCONJUGATE CHEMISTRY

Pegylated Interferons for the Treatment of Chronic Hepatitis C

(2010) Graham R. Foster   DRUGS

Hepatitis C: viral and host factors associated with non-response to pegylated interferon plus ribavirin

(2010) Tarik Asselah et al.   LIVER INTERNATIONAL

Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

(2010) Weikang Tao et al.   MOLECULAR THERAPY

Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells

(2010) M. S. Goldberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-Like Nanoparticles for Small Interfering RNA Delivery to Endothelial Cells

(2009) Seung-Woo Cho et al.   ADVANCED FUNCTIONAL MATERIALS

Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection

(2009) Christoph Sarrazin et al.   GASTROENTEROLOGY

Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery

(2009) J R Viola et al.   GENE THERAPY

Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase

(2009) S.-J. Kim et al.   JOURNAL OF VIRAL HEPATITIS

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

(2009) Akin Akinc et al.   MOLECULAR THERAPY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis

(2009) Y.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

(2008) M. Frank-Kamenetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA