Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-02-23
DOI
10.1038/srep21927
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- LNA-based PCR clamping enrichment assay for the identification of KRAS mutations
- (2017) Edna Efrati et al. Cancer Biomarkers
- Intratumor Heterogeneity of KRAS Mutation Status in Pancreatic Ductal Adenocarcinoma Is Associated With Smaller Lesions
- (2016) Sima S. Nagawkar et al. PANCREAS
- Mutation—The Engine of Evolution: Studying Mutation and Its Role in the Evolution of Bacteria: Figure 1.
- (2015) Ruth Hershberg Cold Spring Harbor Perspectives in Biology
- Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials
- (2015) Rabih Said et al. Oncotarget
- KRAS Codon 12 and 13 Mutations in Relation to Disease-Free Survival in BRAF-Wild-Type Stage III Colon Cancers from an Adjuvant Chemotherapy Trial (N0147 Alliance)
- (2014) H. H. Yoon et al. CLINICAL CANCER RESEARCH
- Sequence Artifacts in DNA from Formalin-Fixed Tissues: Causes and Strategies for Minimization
- (2014) H. Do et al. CLINICAL CHEMISTRY
- Nicotine Promotes Initiation and Progression of KRAS-Induced Pancreatic Cancer via Gata6-Dependent Dedifferentiation of Acinar Cells in Mice
- (2014) Patrick C. Hermann et al. GASTROENTEROLOGY
- KRAS oncogene substitutions in Korean NSCLC patients: Clinical implication and relationship with pAKT and RalGTPases expression
- (2014) Eun Young Kim et al. LUNG CANCER
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Smoking accelerates pancreatic cancer progression by promoting differentiation of MDSCs and inducing HB-EGF expression in macrophages
- (2014) S Kumar et al. ONCOGENE
- Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes
- (2014) Sheli L. Ostrow et al. PLoS Genetics
- Controversies in antiepidermal growth factor receptor therapy in metastatic colorectal cancer
- (2013) Janghee Woo et al. CANCER
- Non-linear dose–response relationship between cigarette smoking and pancreatic cancer risk: Evidence from a meta-analysis of 42 observational studies
- (2013) Li Zou et al. EUROPEAN JOURNAL OF CANCER
- Comparison of Clinical Targeted Next-Generation Sequence Data from Formalin-Fixed and Fresh-Frozen Tissue Specimens
- (2013) David H. Spencer et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- KRAS mutational analysis and immunohistochemical studies can help distinguish pancreatic metastases from primary lung adenocarcinomas
- (2013) Alyssa M Krasinskas et al. MODERN PATHOLOGY
- K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
- (2013) Jonathan M. Ostrem et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Emerging patterns of somatic mutations in cancer
- (2013) Ian R. Watson et al. NATURE REVIEWS GENETICS
- Differences in EGFR and KRAS mutation spectra in lung adenocarcinoma of never and heavy smokers
- (2013) KAZUYA TAKAMOCHI et al. Oncology Letters
- The dominant role of G12C over other KRAS mutation types in the negative prediction of efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in non–small cell lung cancer
- (2013) Ondrej Fiala et al. Cancer Genetics
- Shining a Light on Dark Sequencing: Characterising Errors in Ion Torrent PGM Data
- (2013) Lauren M. Bragg et al. PLoS Computational Biology
- Characterizing and measuring bias in sequence data
- (2013) Michael G Ross et al. GENOME BIOLOGY
- A tale of three next generation sequencing platforms: comparison of Ion torrent, pacific biosciences and illumina MiSeq sequencers
- (2012) Michael Quail et al. BMC GENOMICS
- Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration
- (2012) H. Thorvaldsdottir et al. BRIEFINGS IN BIOINFORMATICS
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF Wild-Type Colorectal Cancers
- (2012) Y. Imamura et al. CLINICAL CANCER RESEARCH
- KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines
- (2012) Isabelle Messner et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Epidemiology, risk factors, and the promotion of pancreatic cancer: Role of the stellate cell
- (2012) Stephen Pandol et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
- (2012) Nathan T. Ihle et al. JNCI-Journal of the National Cancer Institute
- A Pooled Exploratory Analysis of the Effect of Tumor Size and KRAS Mutations on Survival Benefit From Adjuvant Platinum-Based Chemotherapy in Node-Negative Non–Small Cell Lung Cancer
- (2012) Sinead Cuffe et al. Journal of Thoracic Oncology
- Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype
- (2012) Giulio Metro et al. LUNG CANCER
- Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?
- (2012) J DeGregori ONCOGENE
- Lung Adenocarcinoma of Never Smokers and Smokers Harbor Differential Regions of Genetic Alteration and Exhibit Different Levels of Genomic Instability
- (2012) Kelsie L. Thu et al. PLoS One
- Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4)
- (2011) C. Bosetti et al. ANNALS OF ONCOLOGY
- Epidemiology and potential mechanisms of tobacco smoking and heavy alcohol consumption in pancreatic cancer
- (2011) Eric J. Duell MOLECULAR CARCINOGENESIS
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Molecular morphometric analysis shows relative intra-tumoural homogeneity for KRAS mutations in colorectal cancer
- (2011) Liora Farber et al. VIRCHOWS ARCHIV
- Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab
- (2010) Wendy De Roock et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Genetic Mutations Associated with Cigarette Smoking in Pancreatic Cancer
- (2009) A. Blackford et al. CANCER RESEARCH
- Cigarette smoking and K-ras mutations in pancreas, lung and colorectal adenocarcinomas: Etiopathogenic similarities, differences and paradoxes
- (2009) Miquel Porta et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
- (2008) Rafael G. Amado et al. JOURNAL OF CLINICAL ONCOLOGY
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search