Emerging innovations in clinical trial design

The Signature Program: Bringing the Protocol to the Patient

(2015) BP Kang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Brave New World of clinical cancer research: Adaptive biomarker-driven trials integrating clinical practice with clinical research

(2015) Donald A. Berry   Molecular Oncology

The Innovative Medicines Initiative: an engine for regulatory science

(2014) Michel Goldman et al.   NATURE REVIEWS DRUG DISCOVERY

Bayesian adaptive trial design in acute heart failure syndromes: Moving beyond the mega trial

(2012) Sean P. Collins et al.   AMERICAN HEART JOURNAL

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

(2012) Anirudh Prahallad et al.   NATURE

Adaptive clinical trials in oncology

(2011) Donald A. Berry   Nature Reviews Clinical Oncology

I-SPY 2: An Adaptive Breast Cancer Trial Design in the Setting of Neoadjuvant Chemotherapy

(2009) AD Barker et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Bayesian clinical trials at the University of Texas M. D. Anderson Cancer Center

(2009) Swati Biswas et al.   Clinical Trials