Prion infection impairs lysosomal degradation capacity by interfering with rab7 membrane attachment in neuronal cells

The multivesicular body is the major internal site of prion conversion

(2015) Y.-I. Yim et al.   JOURNAL OF CELL SCIENCE

Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101

(2015) P Majumder et al.   Cell Death & Disease

Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation

(2014) Bo Liu et al.   Autophagy

Live imaging of prions reveals nascent PrPScin cell-surface, raft-associated amyloid strings and webs

(2014) Alexander Rouvinski et al.   JOURNAL OF CELL BIOLOGY

Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrPSc Glycoform and Prion Infectivity

(2014) Elizaveta Katorcha et al.   PLoS Pathogens

Prion Infection Impairs Cholesterol Metabolism in Neuronal Cells

(2013) Huanhuan L. Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab7 Is Functionally Required for Selective Cargo Sorting at the Early Endosome

(2013) Emmanuelle Girard et al.   TRAFFIC

Cellular Aspects of Prion Replication In Vitro

(2013) Andrea Grassmann et al.   Viruses-Basel

Prions disturb post-Golgi trafficking of membrane proteins

(2013) Keiji Uchiyama et al.   Nature Communications

Clustering of sialylated glycosylphosphatidylinositol anchors mediates PrP-induced activation of cytoplasmic phospholipase A2and synapse damage

(2012) Clive Bate et al.   Prion

Proteomics Approach to Identify the Interacting Partners of Cellular Prion Protein and Characterization of Rab7a Interaction in Neuronal Cells

(2011) Saima Zafar et al.   JOURNAL OF PROTEOME RESEARCH

Rapid cell-surface prion protein conversion revealed using a novel cell system

(2011) R. Goold et al.   Nature Communications

Autophagy induction by trehalose counter-acts cellular prion-infection

(2009) Yasmine Aguib et al.   Autophagy

Inhibition of cholesterol recycling impairs cellular PrPSc propagation

(2009) Sabine Gilch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prion-induced Activation of Cholesterogenic Gene Expression by Srebp2 in Neuronal Cells

(2009) Christian Bach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy

(2009) Andreas Heiseke et al.   JOURNAL OF NEUROCHEMISTRY

Mutant Prion Protein Expression Is Associated with an Alteration of the Rab GDP Dissociation Inhibitor α (GDI)/Rab11 Pathway

(2009) Tania Massignan et al.   MOLECULAR & CELLULAR PROTEOMICS

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impaired Axonal Transport in Motor Neurons Correlates with Clinical Prion Disease

(2009) Vladimir Ermolayev et al.   PLoS Pathogens

Identification of an Intracellular Site of Prion Conversion

(2009) Zrinka Marijanovic et al.   PLoS Pathogens

Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activation

(2008) Clive Bate et al.   BMC BIOLOGY

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

(2008) Nathalie M. Veith et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cryo-Immunogold Electron Microscopy for Prions: Toward Identification of a Conversion Site

(2008) S. F. Godsave et al.   JOURNAL OF NEUROSCIENCE

Cholesterol Level Regulates Endosome Motility via Rab Proteins

(2007) Hongtao Chen et al.   BIOPHYSICAL JOURNAL