Live imaging of prions reveals nascent PrPScin cell-surface, raft-associated amyloid strings and webs

Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo

(2013) Susan F. Godsave et al.   NEUROBIOLOGY OF AGING

Dissociation of Recombinant Prion Protein Fibrils into Short Protofilaments: Implications for the Endocytic Pathway and Involvement of the N-Terminal Domain

(2012) Xu Qi et al.   BIOCHEMISTRY

Heterogeneous Amylin Fibril Growth Mechanisms Imaged by Total Internal Reflection Fluorescence Microscopy

(2011) Sharadrao M. Patil et al.   BIOCHEMISTRY

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

(2011) Ulrike K Resenberger et al.   EMBO JOURNAL

Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis

(2011) C. G. Hansen et al.   JOURNAL OF CELL SCIENCE

Biological Effects and Use of PrPSc- and PrP-Specific Antibodies Generated by Immunization with Purified Full-Length Native Mouse Prions

(2011) B. Petsch et al.   JOURNAL OF VIROLOGY

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Rapid cell-surface prion protein conversion revealed using a novel cell system

(2011) R. Goold et al.   Nature Communications

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

GPI anchoring facilitates propagation and spread of misfolded Sup35 aggregates in mammalian cells

(2010) Jonathan O Speare et al.   EMBO JOURNAL

Endogenous Proteolytic Cleavage of Disease-associated Prion Protein to Produce C2 Fragments Is Strongly Cell- and Tissue-dependent

(2010) Michel Dron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4

(2010) A. Jen et al.   JOURNAL OF CELL SCIENCE

Membrane molecules mobile even after chemical fixation

(2010) Kenji A K Tanaka et al.   NATURE METHODS

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Octarepeat Region of the Prion Protein Is Conformationally Altered in PrPSc

(2010) Alice Y. Yam et al.   PLoS One

Generation of Cubic Membranes by Controlled Homotypic Interaction of Membrane Proteins in the Endoplasmic Reticulum

(2009) Daniel Lingwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Switching within Individual Amyloid Fibrils

(2009) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advantages of indium-tin oxide-coated glass slides in correlative scanning electron microscopy applications of uncoated cultured cells

(2009) H. PLUK et al.   JOURNAL OF MICROSCOPY

Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

(2009) Abigail S. Haka et al.   MOLECULAR BIOLOGY OF THE CELL

Population context determines cell-to-cell variability in endocytosis and virus infection

(2009) Berend Snijder et al.   NATURE

GM1 structure determines SV40-induced membrane invagination and infection

(2009) Helge Ewers et al.   NATURE CELL BIOLOGY

Natural and synthetic prion structure from X-ray fiber diffraction

(2009) H. Wille et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of an Intracellular Site of Prion Conversion

(2009) Zrinka Marijanovic et al.   PLoS Pathogens

The Prion's Elusive Reason for Being

(2008) Adriano Aguzzi et al.   Annual Review of Neuroscience

Methionine Sulfoxides on PrPSc: A Prion-Specific Covalent Signature†

(2008) Tamar Canello et al.   BIOCHEMISTRY

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

(2008) Debanjan Goswami et al.   CELL

Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy

(2008) Nathalie M. Veith et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cryo-Immunogold Electron Microscopy for Prions: Toward Identification of a Conversion Site

(2008) S. F. Godsave et al.   JOURNAL OF NEUROSCIENCE

Specific Biarsenical Labeling of Cell Surface Proteins Allows Fluorescent- and Biotin-tagging of Amyloid Precursor Protein and Prion Proteins

(2008) Yuzuru Taguchi et al.   MOLECULAR BIOLOGY OF THE CELL

Observing fibrillar assemblies on scrapie-infected cells

(2008) Susanne Wegmann et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Pathologic Prion Protein Infects Cells by Lipid-Raft Dependent Macropinocytosis

(2008) Jehangir S. Wadia et al.   PLoS One