Molecular docking assisted 3D-QSAR study of benzylidene-2,4-thiazolidinedione derivatives as PTP-1B inhibitors for the management of Type-2 diabetes mellitus

Design of Novel Biphenyl-2-thioxothiazolidin-4-one Derivatives as Potential Protein Tyrosine Phosphatase (PTP)-1B Inhibitors Using Molecular Docking Study

(2016) Sant Kumar Verma et al.   Letters in Drug Design & Discovery

Type 2 Diabetes Mellitus: Limitations of Conventional Therapies and Intervention with Nucleic Acid-Based Therapeutics

(2015) Ganesh R. Kokil et al.   CHEMICAL REVIEWS

Docking Study of Novel Pyrrolidine Derivatives as Potential Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors

(2015) Sant Kumar Verma et al.   Letters in Drug Design & Discovery

Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids

(2015) Suresh Thareja et al.   STEROIDS

Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: Synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression

(2014) Syed Nazreen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and docking study of 5-(substituted benzylidene)thiazolidine-2,4-dione derivatives as inhibitors of protein tyrosine phosphatase 1B

(2014) Zengtao Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pharmacological Inhibition of Protein Tyrosine Phosphatase 1B: A Promising Strategy for the Treatment of Obesity and Type 2 Diabetes Mellitus

(2013) E. Panzhinskiy et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular modeling studies of some novel thiazolidinediones with triazole ring

(2013) Yakaiah Chinthala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and molecular modelling studies of novel 3-acetamido-4-methyl benzoic acid derivatives as inhibitors of protein tyrosine phosphatase 1B

(2013) Monika Rakse et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, biological activity and structure–activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells

(2013) Rosaria Ottanà et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches

(2011) Juan José Ramírez-Espinosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Assessment of biological half life using in silico QSPkR approach: A self organizing molecular field analysis (SOMFA) on a series of antimicrobial quinolone drugs

(2011) Honey Goel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Discovery of novel PTP1B inhibitors with antihyperglycemic activity

(2010) Zhang Liu et al.   ACTA PHARMACOLOGICA SINICA

Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators

(2010) Bharat Raj Bhattarai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pharmacology and Chemistry of Diabetes mellitus and Antidiabetic Drugs: A Critical Review

(2010) Ganesh R. Kokil et al.   CURRENT MEDICINAL CHEMISTRY

Recent Advances in Fragment-Based QSAR and Multi-Dimensional QSAR Methods

(2010) Kyaw Zeyar Myint et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus

(2010) Suresh Thareja et al.   MEDICINAL RESEARCH REVIEWS

Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity

(2009) Gabriel Navarrete-Vazquez et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects

(2009) Bharat Raj Bhattarai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure-Based Optimization of Benzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B and Low Molecular Weight Protein Tyrosine Phosphatase

(2009) Rosanna Maccari et al.   ChemMedChem

Self organizing molecular field analysis on a series of human 5α-reductase inhibitors: Unsaturated 3-carboxysteroid

(2009) Suresh Thareja et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

3D-QSAR studies on unsaturated 4-azasteroids as human 5α-reductase inhibitors: A self organizing molecular field analysis approach

(2009) Saurabh Aggarwal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rosiglitazone ameliorates abnormal expression and activity of protein tyrosine phosphatase 1B in the skeletal muscle of fat-fed, streptozotocin-treated diabetic rats

(2005) Yong Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY