Application of a microfluidic-based perivascular tumor model for testing drug sensitivity in head and neck cancers and toxicity in endothelium

The application of 3D cell models to support drug safety assessment: Opportunities & challenges

(2014) Adrian Roth et al.   ADVANCED DRUG DELIVERY REVIEWS

A microfluidic-based platform for tumour spheroid culture, monitoring and drug screening

(2014) K. Kwapiszewska et al.   LAB ON A CHIP

A novel three-dimensional microfluidic platform for on chip multicellular tumor spheroid formation and culture

(2014) Duanping Sun et al.   Microfluidics and Nanofluidics

Application of a microfluidic chip-based 3D co-culture to test drug sensitivity for individualized treatment of lung cancer

(2013) Zhiyun Xu et al.   BIOMATERIALS

Microfluidic cell culture

(2013) Matthias Mehling et al.   CURRENT OPINION IN BIOTECHNOLOGY

Barriers to Drug Delivery in Interventional Oncology

(2013) Rahul A. Sheth et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Three-dimensional cell culture: the missing link in drug discovery

(2012) Susan Breslin et al.   DRUG DISCOVERY TODAY

Application of microfluidic systems in management of head and neck squamous cell carcinoma

(2012) Faiz Tanweer et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

A multilayer microdevice for cell-based high-throughput drug screening

(2012) Chong Liu et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Microfluidic 3D cell culture: potential application for tissue-based bioassays

(2012) XiuJun (James) Li et al.   Bioanalysis

Microfluidic cell coculture methods for understanding cell biology, analyzing bio/pharmaceuticals, and developing tissue constructs

(2011) Mohana Marimuthu et al.   ANALYTICAL BIOCHEMISTRY

Microfluidic array for three-dimensional perfusion culture of human mammary epithelial cells

(2011) Shin-Yi Cindy Chen et al.   BIOMEDICAL MICRODEVICES

A radial microfluidic concentration gradient generator with high-density channels for cell apoptosis assay

(2011) Chun-Guang Yang et al.   LAB ON A CHIP

Microfluidic devices as tools for mimicking the in vivo environment

(2011) Karina Ziółkowska et al.   NEW JOURNAL OF CHEMISTRY

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Current chemotherapies for recurrent/metastatic head and neck cancer

(2010) Yann Molin et al.   ANTI-CANCER DRUGS

Preclinical evaluation of novel, all-in-one formulations of 5-fluorouracil and folinic acid with reduced toxicity profiles

(2010) Tamantha K. Stutchbury et al.   ANTI-CANCER DRUGS

A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids

(2010) Yael Markovitz-Bishitz et al.   BIOMATERIALS

Stimulation of angiogenesis resulting from cooperation between macrophages and MDA-MB-231 breast cancer cells: proposed molecular mechanism and effect of tetrathiomolybdate

(2010) Ulrich Joimel et al.   BMC CANCER

Fundamentals of microfluidic cell culture in controlled microenvironments

(2010) Edmond W. K. Young et al.   CHEMICAL SOCIETY REVIEWS

Tumors on chips: oncology meets microfluidics

(2010) Donald Wlodkowic et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization of the interaction between fibroblasts and tumor cells on a microfluidic co-culture device

(2010) Huipeng Ma et al.   ELECTROPHORESIS

A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies

(2010) Nelita T. Elliott et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

Microfluidic cell culture systems for drug research

(2010) Min-Hsien Wu et al.   LAB ON A CHIP

Advances in chemotherapy for head and neck cancer

(2010) S.A. Bhide et al.   ORAL ONCOLOGY

Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

(2010) K. D. Grugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Chemotherapy in the Management of Patients with Head and Neck Cancer

(2010) Panayiotis Savvides   Seminars in Plastic Surgery

Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids

(2009) Amy Y. Hsiao et al.   BIOMATERIALS

Engineering a scaffold-free 3D tumor model for in vitro drug penetration studies

(2009) Siew-Min Ong et al.   BIOMATERIALS

A microfluidic 3D hepatocyte chip for drug toxicity testing

(2009) Yi-Chin Toh et al.   LAB ON A CHIP

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research

(2009) Tiago G. Fernandes et al.   TRENDS IN BIOTECHNOLOGY

A gel-free 3D microfluidic cell culture system

(2008) Siew-Min Ong et al.   BIOMATERIALS

The future of microfluidic assays in drug development

(2008) Yuan Wen et al.   Expert Opinion on Drug Discovery

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

Current concepts for the management of head and neck cancer: Chemotherapy

(2008) Pol M. Specenier et al.   ORAL ONCOLOGY

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

(2007) Laurent David et al.   Acta Biomaterialia