Placental Protein 13 (PP13) – A Placental Immunoregulatory Galectin Protecting Pregnancy

Role of vesicular trafficking in skeletal dynamics

(2014) Gudrun Stenbeck et al.   CURRENT OPINION IN PHARMACOLOGY

Maternal Serum Placental Growth Factor Isoforms 1 and 2 at 11-13, 20-24 and 30-34 Weeks' Gestation in Late-Onset Pre-Eclampsia and Small for Gestational Age Neonates

(2014) Marta Nucci et al.   FETAL DIAGNOSIS AND THERAPY

Prediction of preeclampsia by placental protein 13 and background risk factors and its prevention by aspirin

(2014) Hamutal Meiri et al.   JOURNAL OF PERINATAL MEDICINE

Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia

(2014) N.G. Than et al.   PLACENTA

Obituary: Hans Bohn, 1928–2014

(2014) Nándor Gábor Than   PLACENTA

The Role of the Carbohydrate Recognition Domain of Placental Protein 13 (PP13) in Pregnancy Evaluated with Recombinant PP13 and the DelT221 PP13 Variant

(2014) Marei Sammar et al.   PLoS One

Maternal plasma concentrations of angiogenic/antiangiogenic factors in the third trimester of pregnancy to identify the patient at risk for stillbirth at or near term and severe late preeclampsia

(2013) Tinnakorn Chaiworapongsa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Effects of Placental Protein 13 on the Cardiovascular System in Gravid and Non-Gravid Rodents

(2013) Sveinbjorn Gizurarson et al.   FETAL DIAGNOSIS AND THERAPY

Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsia

(2013) B. Huppertz et al.   HUMAN REPRODUCTION UPDATE

Evaluation of a rapid and simple placental growth factor test in hypertensive disorders of pregnancy

(2013) Nóra Gullai et al.   HYPERTENSION RESEARCH

B cell receptor-induced Ca2+ mobilization mediates F-actin rearrangements and is indispensable for adhesion and spreading of B lymphocytes

(2013) Máté Maus et al.   JOURNAL OF LEUKOCYTE BIOLOGY

First trimester maternal serum placental protein 13 levels in singleton vs. twin pregnancies with and without severe pre-eclampsia

(2013) Ran Svirsky et al.   JOURNAL OF PERINATAL MEDICINE

Combined Screening for Preeclampsia and Small for Gestational Age at 11–13 Weeks

(2012) Leona C.Y. Poon et al.   FETAL DIAGNOSIS AND THERAPY

First-Trimester Prediction of Preeclampsia in Nulliparous Women at Low Risk

(2012) Leslie Myatt et al.   OBSTETRICS AND GYNECOLOGY

First trimester screening of maternal placental protein 13 for predicting preeclampsia and small for gestational age: In-house study and systematic review

(2012) F.J. Schneuer et al.   PLACENTA

First trimester maternal serum PIGF, free β-hCG, PAPP-A, PP-13, uterine artery Doppler and maternal history for the prediction of preeclampsia

(2012) G. Di Lorenzo et al.   PLACENTA

IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

(2012) M.S. Ahmed et al.   PLACENTA

PP13, Decidual Zones of Necrosis, and Spiral Artery Remodeling—Preeclampsia Revisited?

(2012) Nandor Gabor Than   Reproductive Sciences

Prediction of early and late pre-eclampsia from maternal characteristics, uterine artery Doppler and markers of vasculogenesis during first trimester of pregnancy

(2012) M. Parra-Cordero et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox

(2012) Gerardo R. Vasta et al.   Frontiers in Immunology

Placental protein 13 (PP13/galectin-13) undergoes lipid raft-associated subcellular redistribution in the syncytiotrophoblast in preterm preeclampsia and HELLP syndrome

(2011) Andrea Balogh et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Inflammation and pregnancy: the role of the immune system at the implantation site

(2011) Gil Mor et al.   Annals of the New York Academy of Sciences

Turning the Pyramid of Prenatal Care

(2011) Kypros H. Nicolaides   FETAL DIAGNOSIS AND THERAPY

Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

(2011) Giovanna Ogge et al.   JOURNAL OF PERINATAL MEDICINE

Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways

(2011) Mihaela Anitei et al.   NATURE CELL BIOLOGY

Evaluation of 7 Serum Biomarkers and Uterine Artery Doppler Ultrasound for First-Trimester Prediction of Preeclampsia: A Systematic Review

(2011) Sylwia Kuc et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Placenta-bound and Body Fluid PP13 and its mRNA in Normal Pregnancy Compared to Preeclampsia, HELLP and Preterm Delivery

(2011) M. Sammar et al.   PLACENTA

First-trimester placental protein 13, PAPP-A, uterine artery Doppler and maternal characteristics in the prediction of pre-eclampsia

(2011) A.O. Odibo et al.   PLACENTA

Deep trophoblast invasion and spiral artery remodelling in the placental bed of the lowland gorilla

(2011) R. Pijnenborg et al.   PLACENTA

Deep trophoblast invasion and spiral artery remodelling in the placental bed of the chimpanzee

(2011) R. Pijnenborg et al.   PLACENTA

Screening for Pre-eclampsia–Lessons from Aneuploidy Screening

(2011) H.S. Cuckle   PLACENTA

PP13 as a marker of pre-eclampsia: A two platform comparison study

(2011) N.J. Cowans et al.   PLACENTA

PP13, Maternal ABO Blood Groups and the Risk Assessment of Pregnancy Complications

(2011) Nandor Gabor Than et al.   PLoS One

Prediction of early, intermediate and late pre-eclampsia from maternal factors, biophysical and biochemical markers at 11-13 weeks

(2011) Ranjit Akolekar et al.   PRENATAL DIAGNOSIS

Comparative studies of placentation and immunology in non-human primates suggest a scenario for the evolution of deep trophoblast invasion and an explanation for human pregnancy disorders

(2011) Anthony M Carter   REPRODUCTION

Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia

(2011) Harvey J. Kliman et al.   Reproductive Sciences

Galectins: guardians of eutherian pregnancy at the maternal–fetal interface

(2011) Nandor Gabor Than et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A single rapid point-of-care placental growth factor determination as an aid in the diagnosis of preeclampsia

(2011) Ulla B. Knudsen et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Screening for preeclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women

(2010) François Audibert et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Performance of messenger RNAs circulating in maternal blood in the prediction of preeclampsia at 10-14 weeks

(2010) Antonio Farina et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

PIBF: The Double Edged Sword. Pregnancy and Tumor

(2010) Julia Szekeres-Bartho et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immunology of Pre-Eclampsia

(2010) Christopher W. G. Redman et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Immune System in Pregnancy: A Unique Complexity

(2010) Gil Mor et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Th1/Th2/Th17 and Regulatory T-Cell Paradigm in Pregnancy

(2010) Shigeru Saito et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Evolution of invasive placentation with special reference to non-human primates

(2010) Anthony M. Carter et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

First-trimester placental protein 13 and placental growth factor: markers for identification of women destined to develop early-onset pre-eclampsia

(2010) EJ Wortelboer et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Proteomics Analysis of Bladder Cancer Exosomes

(2010) Joanne L. Welton et al.   MOLECULAR & CELLULAR PROTEOMICS

Innate immune lectins kill bacteria expressing blood group antigen

(2010) Sean R Stowell et al.   NATURE MEDICINE

Stimulation of Syncytium Formation in vitro in Human Trophoblast Cells by Galectin-1

(2010) I. Fischer et al.   PLACENTA

IFPA Gabor Than Award lecture: Transformation of the spiral arteries in human pregnancy: Key events in the remodelling timeline

(2010) L.K. Harris   PLACENTA

Effects of calcium, magnesium, low-dose aspirin and low-molecular-weight heparin on the release of PP13 from placental explants

(2010) Y.-I. Grimpel et al.   PLACENTA

The choriocarcinoma cell line BeWo: syncytial fusion and expression of syncytium-specific proteins

(2010) Kristina Orendi et al.   REPRODUCTION

Review: The Immunomodulatory Roles of Macrophages at the Maternal—Fetal Interface

(2010) Takeshi Nagamatsu et al.   Reproductive Sciences

First trimester markers for the prediction of pre-eclampsia in women with a priori high risk

(2010) Asma Khalil et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Hypertensive disorders in pregnancy: screening by biophysical and biochemical markers at 11-13 weeks

(2010) L. C. Y. Poon et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Ca2+-Dependent Actin Coating of Lamellar Bodies after Exocytotic Fusion: A Prerequisite for Content Release or Kiss-and-Run

(2009) Pika Miklavc et al.   Annals of the New York Academy of Sciences

Galectins in innate immunity: dual functions of host soluble β-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)

(2009) Sachiko Sato et al.   IMMUNOLOGICAL REVIEWS

A novel exonic variant (221delT) in the LGALS13 gene encoding placental protein 13 (PP13) is associated with preterm labour in a low risk population

(2009) S. Gebhardt et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Gabor Than Award Lecture 2008: Pre-eclampsia – From Placental Oxidative Stress to Maternal Endothelial Dysfunction

(2009) T. Cindrova-Davies   PLACENTA

Evidence for Transcriptional Activity in the Syncytiotrophoblast of the Human Placenta

(2009) P.M. Ellery et al.   PLACENTA

Differential Placental Gene Expression in Severe Preeclampsia

(2009) V. Sitras et al.   PLACENTA

Rheological and Physiological Consequences of Conversion of the Maternal Spiral Arteries for Uteroplacental Blood Flow during Human Pregnancy

(2009) G.J. Burton et al.   PLACENTA

PP13 mRNA expression in the cellular component of maternal blood as a marker for preeclampsia

(2009) Hanako Shimizu et al.   PRENATAL DIAGNOSIS

First trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women witha priorihigh risk

(2009) Asma Khalil et al.   PRENATAL DIAGNOSIS

Maternal serum placental protein 13 at 11–13 weeks of gestation in preeclampsia

(2009) Ranjit Akolekar et al.   PRENATAL DIAGNOSIS

A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death

(2009) N. G. Than et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HELLP syndrome: Clinical issues and management. A Review

(2009) Kjell Haram et al.   BMC Pregnancy and Childbirth

First-trimester maternal serum PP13 in the risk assessment for preeclampsia

(2008) Roberto Romero et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Placental protein 13 as an early marker for pre-eclampsia: a prospective longitudinal study

(2008) R Gonen et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells

(2008) J. Klibi et al.   BLOOD

The Effect of Trophoblasts on T Lymphocytes: Possible Regulatory Effector Molecules - A Proteomic Analysis

(2008) Minyue Dong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Longitudinal Determination of Serum Placental Protein 13 during Development of Preeclampsia

(2008) Berthold Huppertz et al.   FETAL DIAGNOSIS AND THERAPY

Placental Origins of Preeclampsia

(2008) Berthold Huppertz   HYPERTENSION

Oxygen, the Janus gas; its effects on human placental development and function

(2008) Graham J. Burton   JOURNAL OF ANATOMY

Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Severe preeclampsia is characterized by increased placental expression of galectin-1

(2008) Nandor Gabor Than et al.   Journal of Maternal-Fetal & Neonatal Medicine

The Two Stage Model of Preeclampsia: Variations on the Theme

(2008) J.M. Roberts et al.   PLACENTA

Placental Endoplasmic Reticulum Stress and Oxidative Stress in the Pathophysiology of Unexplained Intrauterine Growth Restriction and Early Onset Preeclampsia

(2008) G.J. Burton et al.   PLACENTA

Emergence of hormonal and redox regulation of galectin-1 in placental mammals: Implication in maternal-fetal immune tolerance

(2008) N. G. Than et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1

(2008) H. D. Kopcow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PP13 mRNA Expression in Trophoblasts From Preeclamptic Placentas

(2008) Akihiko Sekizawa et al.   Reproductive Sciences

Blood group AB and factor V Leiden as risk factors for pre-eclampsia: A population-based nested case-control study

(2008) Leena M Hiltunen et al.   THROMBOSIS RESEARCH

Placental protein 13 (galectin-13) has decreased placental expression but increased shedding and maternal serum concentrations in patients presenting with preterm pre-eclampsia and HELLP syndrome

(2008) Nandor Gabor Than et al.   VIRCHOWS ARCHIV